What is a pilot scale bioreactor?

What is a pilot scale bioreactor?

The S series pilot scale bioreactors / fermenters are designed for research and development in process scale-up. S series Pilot Scale Bioreactors / Fermenters were designed with the intention to face all the problems related to scaling-up, from the laboratory to the production stage, with maximum easiness.

What is the capacity of pilot scale bioreactor?

Capacity (liter): 1000L to 20000 Liters and above. Condition: New.

What is meant by pilot scale?

What does “pilot scale” mean? A small-scale preliminary study conducted to evaluate feasibility, time, cost, scaling factors, unpredicted results, further develop a process, etc. to properly design and implement a full-scale commercial process.

What is scale-up in bioreactor?

Scale-up is the process of expanding a fermentation process from a smaller-scale fermenter, where operational and production parameters have been studied, to a larger scale. A constant height to diameter ratio for the bioreactors is perhaps the simplest and most common strategy.

What is production fermenter?

In industrial microbiology, the term refers to processes that produce microbial cells (cell biomass), metabolites, enzymes, or recombinant products, and those that modify a compound that is added to the fermentation broth. These processes are carried out under controlled conditions in fermenters or bioreactors.

Which type of fermenter is used in laboratory scale?

It is a large-scale fermenter. Mini fermenter, Stirred laboratory fermenters, and tall tubes are the types of laboratory scale fermenters. Explanation: The mini fermenters consists of 120 ml hypovials (up to 100 ml operating volume).

What is the size of pilot scale fermenter?

The Pilot scale series, in standard configuration, SIP fermenters/bioreactors are available in a wide range of working volumes from 10 – 15000 L liters, with multiple variations and customization options.

What is difference between pilot scale and scale?

➢ A pilot plant can also be defined as the pre-commercial production system which includes new production technology and produces small volumes of new technology-based products (Fig 1). ➢ Scale-up is the process of increasing the batch size or a procedure for applying the same process to different output volumes.

What is a lab scale and pilot scale?

Typically bench scale is in a laboratory and uses systems that can’t handle more than 50L at a time (often much more per day depending on flow rates). Pilot scale is proof of concept at a scaled up size for treating up to 50% of a total actual flow for the application.

What are the various factors which were followed while scaling up process in the bioreactor?

Bioreactor scale-up

• Power-to-volume ratios.
• Height-to-diameter ratios.
• Equipment geometry across scale (ratio of impeller diameter to vessel diameter, impeller blade length, width, and angle)
• Fluid dynamics (type of agitation, number of impellers, tip speed)

Is bioreactor and fermentor the same?

The main difference between bioreactor and fermentor is that the bioreactor is the vessel that facilitates various types of biochemical reactions whereas the fermentor is the vessel that facilitates fermentation. Therefore, fermentor is a type of bioreactor.

What is an industrial scale bioreactor?

Industrial Scale Bioreactors / Fermenters I Series. The Bioreactors – Fermenters of the I Series are highly automated production fermentation systems, available from 250 liters up to 30 m 3, fully customized.

What are bioreactors – fermenters?

The Bioreactors – Fermenters of the I Series are highly automated production fermentation systems, available from 250 liters up to 30 m3, fully customized. The control system technology permits the linking of several units by ETHERNET, for the eventual connection to the supervision system.

What is a steam in place bioreactor?

M Series are steam in place bioreactors – fermenters available in a range of volumes from 30 up to 200 liters. These Bench-top Bioreactors – Fermenters represent the ideal solution for all necessities in the field of research, teaching and small scale production due to their flexibility and simplicity of use.

How big is the fermentation capacity of the I series?

Total voulme from 7.5 up to 20 liters. The Bioreactors – Fermenters of the I Series are highly automated production fermentation systems, available from 300 liters up to 30 m 3, fully customized. The control system technology permits the linking of several units by ETHERNET, for the eventual connection to the supervision system.