What is a pleiotropic gene?
What is a pleiotropic gene?
A pleiotropic gene is a single gene that controls more than one trait. © 2008 Nature Education All rights reserved. During his study of inheritance in pea plants, Gregor Mendel made several interesting observations regarding the color of various plant components.
What are examples of pleiotropic traits?
Deafness and pigmentation in cats, the existence of frizzle traits in cats, Marfan syndrome in humans, sickle cell diseases, Phenylketonuria or PKU, albinism, Austin, and schizophrenia are some of the many examples of pleiotropic.
What’s the difference between pleiotropy and polygenic?
Some people confuse pleiotropy and polygenic inheritance. The major difference between the two is that pleiotropy is when one gene affects multiple characteristics (e.g. Marfan syndrome) and polygenic inheritance is when one trait is controlled by multiple genes (e.g. skin pigmentation).
How are pleiotropic genes inherited?
Alleles of pleiotropic genes are transmitted in the same way as alleles of genes that affect single traits. In these cases, the difference is that the phenotype contains multiple elements. These elements are specified as a package, and there would be both a dominant and recessive version of this package of traits.
What is a Phenocopy in genetics?
Listen to pronunciation. (FEE-noh-KAH-pee) A phenotypic trait or disease that resembles the trait expressed by a particular genotype, but in an individual who is not a carrier of that genotype.
What is pleiotropic gene Class 12?
Pleiotropy can be defined as the expression of multiple traits by a Single Gene. The word ‘Pleiotropy’ is derived from a Greek word which means more ways.
What is pleiotropic gene shaala?
When a single gene controls two (or more) different traits it is called pleiotropic gene and the phenomenon is called pleiotropy or pleiotropism. The phenotypic ratio is 1:2 instead of 3:1 because of the death of recessive homozygote. Two different expressions are produced by a single gene.
What is the difference between polygenic gene and pleiotropic gene?
The main difference between pleiotropy and polygenic inheritance is that in pleiotropy, one gene affects many traits whereas, in polygenic inheritance, many genes affect one trait. Both pleiotropy and polygenic inheritance occur in all living organisms.
Who discovered pleiotropy?
Pleiotropy is defined as the phenomenon in which a single locus affects two or more distinct phenotypic traits. The term was formally introduced into the literature by the German geneticist Ludwig Plate in 1910, 100 years ago.
What is phenocopy with example?
For example, breast cancer in a hereditary breast/ovarian cancer syndrome family member who does not carry the family’s BRCA1 or BRCA2 mutation would be considered a phenocopy.
What is the difference between phenocopy and Genocopy?
Genocopy is a trait that is a phenotypic copy of a genetic trait but is caused by a different genotype. When a genetic mutation or genotype in one locus results in a phenotype similar to one that is known to be caused by another mutation or genotype in another locus, it is said to be a genocopy.
Are most genes technically pleiotropic?
That is, a few genes have extensive pleiotropic effects, but most genes are more limited in their effects on the phenotype. However, nearly all genes have some degree of pleiotropy.
What are some examples of pleiotropy?
Abnormal tall height.
What is pleiotropy in genetics?
Pleiotropy is a condition in which a single gene influences more than one phenotypic trait in an organism.
What are pleiotropic effects?
Medical Definition of Pleiotropic. Pleiotropic: Producing or having multiple effects from a single gene. For example, the Marfan gene is pleiotropic, potentially causing such diverse effects as long fingers and toes (arachnodactyly), dislocation of the lens of the eye, and dissecting aneurysm of the aorta.
