What is a probable etiology of Reye syndrome?

What is a probable etiology of Reye syndrome?

What causes Reye’s syndrome? The exact cause of Reye’s syndrome is unknown, but it most commonly affects children and young adults recovering from a viral infection – for example a cold, flu or chickenpox. In most cases, aspirin has been used to treat their symptoms, so aspirin may trigger Reye’s syndrome.

How many cases of Reye’s syndrome are there?

The incidence of the disorder has dramatically declined in the United States beginning in the late 1980s. Approximately 200 to 550 cases were reported each year in the United States during 1974 to 1984. However, since 1988, fewer than 20 cases have been reported annually.

What body systems does Reye’s syndrome affect?

Reye’s syndrome (RS) is primarily a children’s disease, although it can occur at any age. It affects all organs of the body but is most harmful to the brain and the liver–causing an acute increase of pressure within the brain and, often, massive accumulations of fat in the liver and other organs.

Who is at risk for Reye syndrome?

Reye’s syndrome usually occurs in children who have had a recent viral infection, such as chickenpox or the flu. Taking aspirin to treat such an infection greatly increases the risk of Reye’s. Both chickenpox and the flu can cause headaches. That is why it is important to not use aspirin to treat a child’s headache.

Is Reyes syndrome genetic?

The cause of Reye syndrome is unknown. It usually begins shortly after recovery from a viral infection, such as influenza or chickenpox. About 90% of cases in children are associated with aspirin (salicylate) use. Inborn errors of metabolism are also a risk factor.

Can Reye’s syndrome occur in adults?

The syndrome has rarely been reported to occur in adults over 18 years old. We report the 25th case of Reye’s syndrome occurring in an adult, which initially presented as acetominophen toxicity but was shown to be Reye’s syndrome on histological examination of the liver.

How did Reye’s syndrome get its name?

Reye’s syndrome is named after Australian pathologist R. Douglas Reye, who first reported cases of the condition back in 1963. The exact cause of Reye’s syndrome is unknown, but research has suggested a link between the condition and the use of aspirin.

Why aspirin is contraindicated in Reye’s syndrome?

Reye’s syndrome usually occurs in children who have had a recent viral infection, such as chickenpox or the flu. Taking aspirin to treat such an infection greatly increases the risk of Reye’s. Both chickenpox and the flu can cause headaches. That’s why it’s important to not use aspirin to treat a child’s headache.

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