What is an ER positive tumor?
What is an ER positive tumor?
Hormone Receptor-Positive Breast Cancer About 80% of all breast cancers are “ER-positive.” That means the cancer cells grow in response to the hormone estrogen. About 65% of these are also “PR-positive.” They grow in response to another hormone, progesterone.
What is node negative cancer?
Listen to pronunciation. (node-NEH-guh-tiv) Cancer that has not spread to the lymph nodes.
Is it better to have HER2-positive or negative?
Is HER2-positive breast cancer good or bad? HER2-positive cancer tends to be poorer in terms of prognosis than HER2-negative cancer because: It grows faster. It is more likely to spread to the lymph nodes fast.
Can HER2 negative Be Cured?
When you have HER2-negative advanced (metastatic) breast cancer, treatment usually focuses on managing your disease, not curing the cancer. The goal is to help you live longer and have a better quality of life. This type of cancer is most often treated with systemic therapy.
What does lymph node negative mean?
Lymph node status shows whether or not the lymph nodes in the underarm area (axillary lymph nodes) contain cancer: Lymph node-negative means none of the axillary lymph nodes contain cancer. Lymph node-positive means at least one axillary lymph node contains cancer.
What is the difference between ER positive and ER positive breast cancer?
Cancerous cells may have none, one, or both receptors. Breast cancers that have estrogen receptors are called ER-positive (or ER+). Those with progesterone receptors are referred to as PR-positive (or PR+). In addition to hormone receptors, some breast cancers have high levels of a growth-promoting protein called HER2/neu.
What is the prognosis of node-negative breast cancer?
Risk of mortality of node-negative, ER/PR/HER2 breast cancer subtypes in T1, T2, and T3 tumors T1a tumors have the same risk of mortality regardless of ER/PR/HER2 subtype, and ER and PR negativity plays a stronger role in survival than HER2 positivity for tumors of all size.
What is the prognosis of Stage 4 ER-positive breast cancer?
Although at this point the cancer is incurable, a woman with stage 4 ER-positive breast cancer may respond well to hormone therapies that can extend life for many years. Most women with early stage breast cancer will have surgery before starting hormone therapy.
What treatment options are available for ER-positive breast cancer?
What treatment options are available is highly dependent on the test results. If you have ER-positive breast cancer, your cancer cells grow in the presence of the hormone estrogen. Estrogen occurs naturally in the body. Drugs that interfere with estrogen’s ability to promote cancer cell growth are used to treat ER-positive breast cancers.
