What is CKD-EPI eGFR?
What is CKD-EPI eGFR?
The CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation was developed in an effort to create a more precise formula to estimate glomerular filtrate rate (GFR) from serum creatinine and other readily available clinical parameters, especially at when actual GFR is >60 mL/min per 1.73m2.
What is the normal range for eGFR in blood tests?
A normal eGFR is 60 or more. If your eGFR is less than 60 for three months or more, your kidneys may not be working well.
What is GFR EST Glomer Filtrat?
A glomerular filtration rate (GFR) is a blood test that checks how well your kidneys are working. Your kidneys have tiny filters called glomeruli. These filters help remove waste and excess fluid from the blood. A GFR test estimates how much blood passes through these filters each minute.
When would you use CKD-EPI equation?
A laboratory that reports eGFR numeric values > 60 mL/min/1.73 m2 should use the CKD-EPI equation, because the CKD-EPI equation is more accurate for values > 60 mL/min/1.73 m2 than is the MDRD Study equation.
What is CKD EPI creatinine equation?
The CKD-EPI equation, expressed as a single equation, is GFR = 141 × min(Scr/κ, 1)α × max(Scr/κ, 1)-1.209 × 0.993Age × 1.018 [if female] _ 1.159 [if black], where Scr is serum creatinine, κ is 0.7 for females and 0.9 for males, α is -0.329 for females and -0.411 for males, min indicates the minimum of Scr/κor 1, and …
What causes kidney damage?
Kidneys can become damaged from a physical injury or a disease like diabetes, high blood pressure, or other disorders. High blood pressure and diabetes are the two most common causes of kidney failure. Kidney failure does not happen overnight. It is the end result of a gradual loss of kidney function.
What is needed to calculate eGFR?
Estimating GFR begins with a simple serum creatinine blood test. If you’re using our GFR calculator, your eGFR is calculated using the results of your blood test, along with your age, ethnicity, and gender. When your eGFR is calculated by your doctor, weight and body size may also be factored into your eGFR.
What does CKD-EPI stand for?
Comparative performance of the CKD epidemiology collaboration ( CKD-EPI) and the modification of diet in renal disease (MDRD) study equations for estimating GFR levels above 60 mL/min/1.73 m2.
What is the difference between the CKD-EPI and MDRD equations?
In comparison with the CKD-EPI equation, the MDRD equation augmented the trend of increasing prevalence of CKD, showed a weaker association with risk factors and tended to assign impaired renal function to individuals without an excess of cardiovascular risk factors.
What is the CKD-EPI equation calculator for creatinine?
Read more about creatinine standardization. This CKD-EPI equation calculator should be used when S cr is reported in mg/dL. This equation is recommended when eGFR values above 60 mL/min/1.73 m² are desired. GFR = 141 × min (S cr /κ, 1) α × max (S cr /κ, 1) -1.209 × 0.993 Age × 1.018 [if female] × 1.159 [if African American]
When should I use the NIDDK’s CKD-EPI calculator?
The NIDDK’s calculators rely on creatinine determinations which are isotope dilution mass spectrometry (IDMS) traceable. All laboratories should be using creatinine methods calibrated to be IDMS traceable. Read more about creatinine standardization . This CKD-EPI equation calculator should be used when S cr is reported in mg/dL.
