What is CRP agglutination test?
What is CRP agglutination test?
PRINCIPLE. CRP-Latex Test is a rapid slide agglutination procedure based on a modification of the latex fixation method1, developed for the direct detection and semi-quantitation of C-reactive protein (CRP) in serum.
What is being detected in CRP latex test?
A c-reactive protein test measures the level of c-reactive protein (CRP) in your blood. CRP is a protein made by your liver. It’s sent into your bloodstream in response to inflammation. Inflammation is your body’s way of protecting your tissues if you’ve been injured or have an infection.
What are the limitations of CRP latex slide test?
Limitations of CRP Test The strength of the agglutination reaction is not indicative of the CRP concentration. Weak reactions may occur with slightly elevated or markedly elevated concentrations. A prozone phenomena (antigen excess) may cause false negatives.
What is the speed of mechanical rotator to observe for agglutination in CRP testing?
80-100 r.p.m.
Place the slide on a mechanical rotator at 80-100 r.p.m. for 2 minutes. False positive results could appear if the test is read later than two minutes.
What does it mean if your C reactive protein is high?
A high level of CRP in the blood can be a marker of inflammation. A wide variety of conditions can cause it, from an infection to cancer. High CRP levels can also indicate that there’s inflammation in the arteries of the heart, which can mean a higher risk of heart attack.
Is CRP elevated in autoimmune disease?
Significantly high CRP levels of more than 350 milligrams per liter (mg/L) are nearly always a sign of a serious underlying medical condition. The most common cause is a severe infection, but a poorly controlled autoimmune disease or severe tissue damage can also lead to high CRP levels.
What is high-sensitivity C-reactive protein (hs-CRP)?
High-sensitivity C-reactive protein is produced by the body when blood-vessel walls are inflamed. The higher your levels of hs-CRP, the higher your levels of inflammation tend to be. But before we go any further, it’s important to distinguish between acute inflammation and chronic inflammation. Inflammation can be a very good thing.
Are high-sensitivity assays for CRP available in clinical laboratories?
Based in part on these data, high-sensitivity assays for CRP have become available in standard clinical laboratories.
What does the hs-CRP test measure?
This protein measures general levels of inflammation in your body. The hs-CRP can be used to find the risk for heart disease and stroke in people who don’t already have heart disease. The hs-CRP test is different than the standard CRP test.
What are the risks of a high hs-CRP level?
People who have a known high risk of having a heart attack should seek treatment and preventive measures regardless of how high their hs-CRP level is. A CRP test or an hs-CRP test poses little risk. As with any blood draw, you might have some soreness or bruising around the draw site. The site can become infected, but that’s rare.
