What is DXM (dextromethorphan)?
What is DXM (dextromethorphan)?
Dextromethorphan (DXM or DM) is a medication most often used as a cough suppressant in over-the-counter cold and cough medicines.
What is the mechanism of action of dextromethorphan?
This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. Dextromethorphan is a 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a- (epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration.
What is the best way to take dexdextromethorphan?
Dextromethorphan comes as a liquid-filled capsule, a chewable tablet, a dissolving strip, a solution (liquid), an extended-release (long-acting) suspension (liquid), and a lozenge to take by mouth. It is usually taken every 4 to 12 hours as needed. Follow the directions on the package or prescription label…
Does dextromethorphan help with coughs?
Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery. Dextromethorphan is in a class of medications called antitussives. It works by decreasing activity in the part of the brain that causes coughing.
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What are the side effects of dexdextromethorphan?
Dextromethorphan is a safe and effective cough suppressant with minimal adverse effects when used at recommended dosages; however, the drug can have euphoric, stimulant, and dissociative effects at higher dosages. Abuse of the drug for its euphoric and dissociative effects occurs mainly in adolescents.
Can you get addicted to dextromethorphan?
In many documented cases, dextromethorphan has produced psychological dependence in people who used it recreationally. However, it does not produce physical addiction, according to the WHO Committee on Drug Dependence. It is considered less addictive than the other common weak opiate cough suppressant, codeine.
How long does it take for dexdextromethorphan to work?
Dextromethorphan is rapidly absorbed from the GI tract and exerts its antitussive effect in 15-30 minutes after oral administration. The duration of action is approximately 3-6 hours with conventional dosage forms.
What is dextromethorphan cough syrup used for?
Cough suppression. The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (such as commonly accompanies the flu and common cold), as well as those resulting from inhaled particle irritants.
