What is effective refractory period in heart?

What is effective refractory period in heart?

The effective refractory period (ERP) is the longest premature coupling interval (S1-S2) at a designated stimulus amplitude (usually 2× diastolic threshold) that results in failure of propagation of the premature impulse through a tissue. From: Clinical Arrhythmology and Electrophysiology, 2009.

What increases effective refractory period?

Sodium-channel blockers (particularly Class IA) also increase the ERP by prolonging the inactivation state of fast-sodium channels. Drugs that increase the ERP can be particularly effective in abolishing reentry currents that lead to tachyarrhythmias.

What is AV nodal effective refractory period?

The effective refractory period (ERP) of the AV. node was the longest A,A2 interval at which A2 failed. to depolarize the His bundle. The ERP of the atrium was the longest S,S2 interval.

What is the difference between effective refractory period and absolute refractory period?

The absolute refractory period is a period where it is completely impossible for another action potential to be activated, regardless of the size of the trigger (stimulus). In the cardiovascular mechanism, this refractory period is sometimes called effective refractory period (ERP).

Which medication prolongs the effective refractory period?

Class III antiarrhythmic drugs act by blocking repolarising currents and thereby prolong the effective refractory period of the myocardium. This is believed to facilitate termination of re-entry tachyarrhythmias. This class of drugs is developed for treatment of both supraventricular and ventricular arrhythmias.

Which drugs prolong refractory period?

Amiodarone (Cordarone, Pacerone) It prolongs the action potential and refractory period in myocardium and inhibits adrenergic stimulation. Before administration, control ventricular rate and congestive heart failure (if present) with digoxin.

What is the function of the refractory period?

After an action potential initiates, the cardiac cell is unable to initiate another action potential for some duration of time (which is slightly shorter than the “true” action potential duration). This period of time is referred to as the refractory period, which is 250ms in duration and helps to protect the heart.

How do I shorten my refractory period?

You can shorten refractory period by improving several physical and psychological parts of your sexuality and body. Improving your cardiovascular system will provide you with the physical support you need to get another erection shortly after orgasm.​.

What occurs during the refractory period?

refractory period. the period of depolarization and repolarization of the cell membrane after excitation; during the first portion (absolute refractory period), the nerve or muscle fiber cannot respond to a second stimulus, whereas during the relative refractory period, it can respond only to a strong stimulus.

How long is your refractory period?

The length of refractory period varies from person to person. For some men, this period is just about 15 minutes long and for others, it might be as long as 24 hours. Some people can also achieve multiple orgasms.

What accounts for a long refractory period in cardiac muscle?

Muscle fiber (cell) in the ventricular tissue of the heart, specialized for conducting an action potential to the myocardium. What accounts for the long refractory period of cardiac muscle? Calcium channels are to slow to close and potassium channels are slow to open.