What is Ehlers-Danlos syndrome in animals?

What is Ehlers-Danlos syndrome in animals?

Ehlers–Danlos syndrome (EDS), also called cutaneous asthenia 1, 2, is an uncommon connective tissue disease characterized by abnormal collagen structure in dogs. EDS inheritance in dogs is autosomal dominant 1, 3, but recessive forms have been postulated 3 and most frequently seen in Dachshunds, Boxers, St.

What is the life expectancy of someone with EDS?

People affected by vascular EDS have a median life expectancy of 48 years and many will have a major event by age 40. The lifespan of people with the kyphoscoliosis form is also decreased, largely due to the vascular involvement and the potential for restrictive lung disease.

Can animals have EDS?

Ehler Danlos Syndrome is a very rare, inherited disease. This disease affects people and animals. In dogs with EDS, there is abnormal production or breakdown of collagen.

How does Ehlers-Danlos affect connective tissue?

Ehlers-Danlos syndrome is a group of inherited disorders that affect your connective tissues — primarily your skin, joints and blood vessel walls. Connective tissue is a complex mixture of proteins and other substances that provide strength and elasticity to the underlying structures in your body.

Can animals have hypermobility?

This is caused by a genetic defect in the production of collagen. Not only is this condition recognized in humans but also dogs, sheep, cattle, mink, pigs and cats. Another interesting finding in humans is that joint hypermobility is often associated with anxiety disorders some studies dating back to the 1980s.

Can dogs have connective tissue disorders?

Clinical changes observed in a heritable connective tissue disease of dogs and mink include fragility, hyperextensibility, and laxity of the skin. Skin fragility is the most severe and consistent change noted in the affected dogs and mink.

What triggers EDS?

Causes. EDS happens when your body doesn’t make a protein called collagen in the right way. Collagen helps form the connections that hold your body’s bones, skin, and organs together. If there’s a problem with it, those structures can be weak and more likely to have problems.

Is Ehlers-Danlos a terminal illness?

Vascular Ehlers-Danlos syndrome is a rare, life-threatening, autosomal dominant variant of EDS, resulting from mutations in COL3A1 gene. Affected individuals are prone to serious and potentially fatal complications, especially vascular, intestinal, and uterine ruptures.

What is feline Ehlers-Danlos Syndrome?

Feline Cutaneous Asthenia in Cats. Feline cutaneous asthenia (FCA), also known as Ehlers-Danlos syndrome, is a disease characterized by deficient levels of collagen, the protein molecule necessary for providing strength and elasticity to the skin and ligaments, along with much of the rest of the body.

Why is EDS called zebra?

The EDS community adopted the zebra as its mascot because “sometimes when you hear hoofbeats, it really is a zebra.” In this spirit, The Ehlers-Danlos Society includes patients, caregivers, health care professionals and supporters working “towards a time when a medical professional immediately recognizes someone with …

Is Ehlers-Danlos an autoimmune?

A much rarer group of connective tissue disorders is called Ehlers-Danlos syndrome. Unlike the diseases noted above, Ehlers-Danlos syndrome is not an autoimmune condition, it’s an inherited disorder.

Can dogs hyperextend their legs?

When a dog falls and lands primarily on his front legs, the force of landing can cause the carpus to hyperextend (bend more than usual), tearing the ligaments that stabilize this joint. Once these ligaments are torn, stability is lost. This condition is most common in large breed dogs.