What is Jaffe method?

What is Jaffe method?

The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine.

What is Kdigo stand for?

Acute kidney injury based on KDIGO (Kidney Disease Improving Global Outcomes) criteria in patients with elevated baseline serum creatinine undergoing cardiac surgery.

What does a creatinine test test for?

A creatinine test is a measure of how well your kidneys are performing their job of filtering waste from your blood. Creatinine is a chemical compound left over from energy-producing processes in your muscles. Healthy kidneys filter creatinine out of the blood. Creatinine exits your body as a waste product in urine.

What is the principle involved in the Jaffe reaction?

The method is based on the Jaffe reaction. Creatinine reacts with picrate ion formed in alkaline medium to develop a red-orange colour. The colour produced from the sample is then compared in a colorimeter at wavelength of 505 nm with that produced by a known amount of creatinine under the same condition.

Does picric acid react with NaOH?

3a, NaOH concentration of 0.5% reached a maximum absorbance of the creatinine-picric acid complex. The absorbance decreased along with the increasing NaOH concentration due to the formation of sodium picric precipitate under high alkaline condition 4 .

What is KDIGO guideline?

KDIGO is the global nonprofit organization developing and implementing evidence-based clinical practice guidelines in kidney disease. Go to All Guidelines. KDIGO guidelines translate global scientific evidence into practical recommendations for clinicians and patients.

What is _potassium hydroxide (KOH)?

Potassium hydroxide, also known as _lye_ is an inorganic compound with the chemical formula _KOH_. Also commonly referred to as _caustic potash_, it is a potent base that is marketed in several forms including pellets, flakes, and powders.

What does NKDEP stand for?

The National Kidney Disease Education Program (NKDEP) (2000-2019) promoted evidence-based interventions to improve understanding, detection, and management of kidney disease, including identification of patients at greatest risk for progression to kidney failure.

What is the hazard rating for potassium hydroxide?

Hazard Rating Key: 0=minimal; 1=slight; 2=moderate; 3=serious; 4=severe f Potassium Hydroxide can affect you when inhaled and by passing through the skin. f Potassium Hydroxide is a HIGHLY CORROSIVE CHEMICAL and contact can severely irritate and burn the skin and eyes leading to eye damage.

What is the chemical formula for potassium hydroxide?

Potassium hydroxide is an inorganic compound which is denoted by the chemical formula KOH. Potassium hydroxide is also known as caustic potash, lye, and potash lye. This alkali metal hydroxide is a very powerful base. In its aqueous form, its appearance is that of a clear solution.

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