What is leukoreduction of blood?
What is leukoreduction of blood?
From Wikipedia, the free encyclopedia. Leukoreduction is the removal of white blood cells (or leukocytes) from the blood or blood components supplied for blood transfusion. After the removal of the leukocytes, the blood product is said to be leukoreduced.
What is leukoreduction and when is it done?
The leukoreduction filter traps the white blood cells and is discarded. The red blood cells and other important blood components collect in a new bag (at the bottom). Today’s technology allows removal of more than 99.99 per cent of donor leukocytes.
How is leukoreduction done?
Leukoreduction can be performed by filtration prior to component storage (prestorage leukoreduction) or during the transfusion (bedside filtration). For apheresis-derived platelets, leukoreduction is often performed by cell separation during the apheresis collection.
Why do we use Leukoreduced blood?
Leukoreduced blood and components are used to decrease the incidence of febrile transfusion reactions: to decrease the risk of cytomegalovirus (CMV) transmission to CMV negative immunocompromised or pregnant recipients, and to decrease sensitization to human leukocyte antigens (HLA) (important for transplant patients …
What is leukoreduction filtration?
Abstract. Leukoreduction of blood products is a technique used to prevent leukocyte-induced transfusion reactions. Filters currently used for human blood products achieve at least a 99.9% reduction in leukocyte numbers per unit (450 mL) of blood.
Why are platelets given to patients?
Platelet transfusions. Platelets are cells that help to stop bleeding. Some cancers or cancer treatments can lead to low platelets and you may need a platelet transfusion.
What is a leukoreduction filtration?
Can platelets be Leukoreduced?
Leukoreduced Blood Products Leukoreduction techniques can be used for RBC and platelet units. The units are filtered before storage or at the bedside.
What is a leukoreduction filter?
Why is blood leukocyte reduced?
The process of removing white blood cells from a blood product prior to transfusion, primarily by filtration. There are three well-accepted reasons to leukocyte-reduce blood products: Prevention of alloimmunization to foreign HLA antigens. Prevention of febrile nonhemolytic transfusion reactions.
What are platelets used to treat?
Platelets are a blood component used to treat low blood platelet counts (thrombocytopenia) or platelet dysfunction, to treat active platelet-related bleeding, or as prophylaxis in those at serious risk of bleeding.
