What is lofepramine side effects?

What is lofepramine side effects?

Lofepramine is not addictive, but if you stop taking the medicine suddenly, you may experience unpleasant physical feelings. Symptoms are fairly common and include nausea, insomnia, diarrhoea, excess salivation and anxiety. Reducing the dose of lofepramine slowly may make these symptoms less severe.

How long is lofepramine in system?


Clinical data
Metabolism Hepatic (via cytochrome P450, including CYP2D6)
Metabolites Desipramine (major)
Elimination half-life Up to 5 hours; 12–24 hours (active metabolites)
Excretion Urine, feces (mostly as metabolites)

Is lofepramine an anticholinergic?

Comparative clinical trials have shown that lofepramine is associated with a low incidence of anticholinergic side-effects.

What does lofepramine do to the brain?

Lofepramine works by stopping the serotonin and noradrenaline that has been released from being reabsorbed back into the nerve cells in the brain. This helps to prolong their effects and over time this helps to lighten mood and relieve depression.

What is the half-life of lofepramine?

Antidepressants by generic name and key characteristics

Generic name Trade names (UK) Half-life
lofepramine Lomont 12 to 24 hours
mianserin n/a 6 to 39 hours
mirtazapine Zispin 20 to 40 hours
moclobemide Manerix 2 to 4 hours

Does lofepramine make you sleepy?

Lofepramine can make you feel sleepy. Do not drive and do not or use tools or machines while affected. Do not drink alcohol. Tell your doctor if you experience any troublesome side-effects.

What is the half life of Lofepramine?

Does Lofepramine make you sleepy?

Is Lofepramine a sedative?

It has been widely compared with other tricyclic antidepressants, and in general its antidepressant efficacy is equivalent. Lofepramine is not sedating; early in treatment it can be experienced as activating, an effect which some depressed patients find unpleasant.

What is the side effect of paroxetine?

Nausea, drowsiness, dizziness, trouble sleeping, loss of appetite, weakness, dry mouth, sweating, blurred vision, and yawning may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What is the half life of lofepramine?


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