What is metastatic carcinoma of cervix?

What is metastatic carcinoma of cervix?

Metastasis in carcinoma cervix can occur via lymphatic spread or hematogenous spread. Hematogenous spread in carcinoma cervix is more common in advanced stage and mostly occurs through venous plexus or the paracervical veins. The common site of distant metastasis includes lung, liver, bones, and supraclavicular nodes.

What causes squamous cell carcinoma of the cervix?

What causes squamous cell carcinoma? Almost all cases of squamous cell carcinoma and HSIL in the cervix are a result of the normal squamous cells in the cervix becoming infected with a high-risk type of virus called human papillomavirus (HPV).

What is the most common histologic form of cervical cancer?

Squamous cell carcinoma (SCC) is the predominant histological type accounting for three-fourths of all cervical cancers. Adenocarcinoma and adenosquamous cell carcinoma represent 10–15%, and other or unspecified histology represent the remaining 10–15% [2,3].

Where does cancer of the cervix spread to?

The most common places for cervical cancer to spread is to the lymph nodes, liver, lungs and bones.

When is a radical hysterectomy performed?

A radical hysterectomy is usually carried out to remove and treat cancer when other treatments, such as chemotherapy and radiotherapy, are not suitable or have not worked. During the procedure, the body of your womb and cervix is removed, along with: your fallopian tubes. part of your vagina.

How is squamous cell carcinoma of the cervix treated?

Traditionally, radical hysterectomy or radiation therapy alone has been accepted as standard treatment for early-stage invasive cervical cancer, and locally advanced cancer has been treated by radiotherapy alone consisting of a combination of high-dose-rate intracavitary brachytherapy (ICBT) and external beam …

Is squamous cell carcinoma of cervix aggressive?

Small cell cancers are sometimes found alongside other more common types of cervical cancers, such as squamous cell carcinoma and adenocarcinoma. Due to their aggressive nature, they tend to be diagnosed at advanced stages, when they have spread to the lymph nodes or other areas of the body.

Is cervical cancer fast growing?

Cervical cancer is a slow-growing malignancy. In fact, once cells in the cervix begin to undergo abnormal changes, it can take several years for the cells to grow into invasive cervical cancer.

What is cervical carcinoma in situ?

Cervical carcinoma in situ is also referred to as stage 0 cervical cancer. It’s noninvasive, which means the cancerous cells are confined to the surface of your cervix and haven’t penetrated more deeply into the tissues. The cervix is the narrow, lower part of the uterus. It’s the passageway from the uterus to the vaginal canal.

What is squamous cell carcinoma of the endocervix?

Squamous cell carcinomas most often begin in the transformation zone (where the exocervix joins the endocervix). Most of the other cervical cancers are adenocarcinomas. Adenocarcinomas are cancers that develop from glandular cells. Cervical adenocarcinoma develops from the mucus-producing gland cells of the endocervix.

What is the origin of cervical cancer?

The junction between these two cells types, called the transformation zone, is the usual site of origin of Cervical Cancer The development of Cervical Cancer occurs slowly and the process of pre-cancerous changes (dysplasia) leading onto invasive cancer, generally takes place over years.

What are adenocarcinomas of cervix?

After squamous cell cancers, Adenocarcinomas of Cervix are the second most common type of tumors, affecting the cervix. This differentiation is based on the appearance of cells, when observed under a microscope. Screening with Pap smear helps in early detection of pre-cancers and cancers.

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