What is metastatic choriocarcinoma?
What is metastatic choriocarcinoma?
Choriocarcinoma is a malignant proliferation of trophoblasts that complicates a normal or abnormal pregnancy. Intraparenchymal brain metastases from choriocarcinoma occur in 10-20 % of the cases and are often haemorrhagic.
What are the signs and symptoms of choriocarcinoma?
Symptoms of choriocarcinoma which has spread
- lungs – you might have a cough, difficulty breathing and sometimes chest pain.
- vagina – you might have heavy bleeding, and your doctor might be able to feel a lump (nodules) in your vagina.
- abdomen – you might have abdominal pain.
What is the drug of choice for choriocarcinoma?
If you have high risk PTD or choriocarcinoma, you might have the drug methotrexate by drip into a vein (intravenous infusion). This is followed a week later by the drugs actinomycin and etoposide. Or you may have a combination of chemotherapy drugs called EMA-CO.
Can choriocarcinoma be cured?
Choriocarcinoma is a rare type of cancer. It usually develops from cells that remain inside the body after a pregnancy. In the vast majority of cases, choriocarcinoma is curable. The outlook for people with this condition is generally very good, although it can sometimes cause complications.
Can choriocarcinoma spread to lungs?
INTRODUCTION: Choriocarcinoma is a rare malignant germ cell tumor with a 80-85% rate of lung metastasis (1). Chemotherapy is highly effective, resulting in cure rates of approximately 90% (3).
Is methotrexate used in choriocarcinoma?
Conclusion: Methotrexate is routinely used in a parenteral intramuscular fashion for the treatment of gestational choriocarcinoma. Physicians should be aware that, in very limited situations, oral methotrexate in combination with hysterectomy still could offer a patient successful treatment for stage III GTN.
How is choriocarcinoma treated?
Doctors typically treat gestational choriocarcinoma with chemotherapy. It works by either killing the cancerous cells or stopping the tumor from growing. Some people might need more than one type of chemotherapy. If the tumor has spread, the person might also need radiation therapy and surgery.
