What is micro emulsion method?
What is micro emulsion method?
Controllable particles sizes of starch nanoparticles were synthesized via a precipitation in water-in-oil microemulsion approach. Microemulsion method offers the advantages of ultralow interfacial tension, large interfacial area, and being thermodynamically stable and affords monodispersed nanoparticles.
What is micro emulsion Slideshare?
Introduction Microemulsion is an isotropic mixture of oil, surfactant, Cosurfactant and drug. Upon mild agitation followed by dilution in aqueous media, such as gastrointestinal (GI) fluids, the systems can form fine oil in water (O/W) Microemulsions which usually have a droplet size less than 100 nm.
What is micro emulsion in physical pharmaceutics?
The term “micro emulsion” refers to a thermodynamically stable isotropically clear dispersion of two immiscible liquids, such as oil and water, stabilized by an interfacial film of surfactant molecules.
What is micro emulsified?
Microemulsions. Microemulsions are composed of nanometer-sized droplets of an immiscible liquid dispersed in another liquid. The components of a microemulsion are water, oil, a surfactant, and a cosurfactant, which is usually a short-chain alcohol.
What is the size of microemulsion?
A microemulsion is a thermodynamically stable fluid. It is different from kinetically stable emulsions which will be break into oil and water over time. The particle size of microemulsions ranges from about 10 nm to 300 nm. Because of the small particle sizes, microemulsions appear as clear or translucent solutions.
How do you make micro emulsions?
The formulation is prepared above the melting point of the lipid to form the microemulsion. Lipid (fatty acid or glycerides) is dissolved; surfactant, cosurfactant, and active ingredient solution in water is heated to the same temperature and the resulting mixture is added to the lipids.
How do you make a micro emulsion?
Why is microemulsion used?
Microemulsions have many commercially important uses: Water-in-oil microemulsions for some dry cleaning processes. Floor polishers and cleaners. Personal care products.
Which properties is characteristic of microemulsion?
Microemulsions are thermodynamically stable, fluid, optically clear dispersions of two immiscible liquids.
What is emulsion and microemulsion?
Emulsions and microemulsions are both stable dispersions of oil-in-water or water-in-oil. Emulsions are stable dispersions of immiscible liquids, but they are not thermodynamically stable. We say that they are kinetically stable. These type of dispersions are sometimes called macroemulsions.
How do you prepare multiple emulsions?
Methods of Preparation Multiple emulsions are best prepared by re- emulsification of primary emulsion. The following are the method of multiple emulsions: Two Steps Emulsification (Double Emulsification) Phase Inversion Technique (One Step Technique) 29 30.
How do you prepare microemulsions?
PREPARATION METHODS OF MICROEMULSIONS : Following are the different methods used for the preparation of the microemulsions : 1) Phase titration method 2) Phase inversion method omega college of pharmacy. 14 15. PHASE-TITRATION METHOD : 1. Dilution of an oil-surfactant mixture with water. [W/O] 2.
What is internal and external phase in emulsions?
Internal Phase or External Phase in Emulsions The dispersed liquid is known as the Internal or Discontinuous phase. The droplet phase is called the dispersed phase or internal phase whereas the dispersion medium is known as the External or Continuous phase The liquid in which droplets are dispersed is called the external or continuous phase. 7.
What is the difference between macro and micro emulsions?
Appearance Most of the emulsions are opaque (white). Microemulsions are transparent. Stability They are stable but coalesce finally. More thermodynamically stable than macro emulsions. Preparation Require intense agitation for their formation. Generally obtained by gentle mixing of ingredients.
