What is mild Hypergammaglobulinemia?

What is mild Hypergammaglobulinemia?

Hypogammaglobulinemia is a problem with the immune system that prevents it from making enough antibodies called immunoglobulins. Antibodies are proteins that help your body recognize and fight off foreign invaders like bacteria, viruses, and fungi. Without enough antibodies, you’re more likely to get infections.

Is hypogammaglobulinemia a cancer?

Hypogammaglobulinemia is a problem with the immune system in which not enough gamma globulins are produced in the blood (thus hypo- + gamma + globulin + -emia). This results in a lower antibody count, which impairs the immune system, increasing risk of infection….

Hypogammaglobulinemia
Specialty Hematology

What medications can cause Hypogammaglobulinemia?

Hypogammaglobulinemia may result from other anticonvulsants and anti-inflammatory medications, including valproic acid, phenytoin, gold, sulfasalazine, chloroquine, penicillamine, fenclofenac, hydantoin, zonisamide, lamotrigine, and cyclosporine A (1, 4, 5, 9).

How is hypogammaglobulinemia diagnosed?

Complete blood count (CBC) The CBC may indicate lymphopenia or lymphocytosis, which may be seen with secondary causes of hypogammaglobulinemia (intestinal lymphangiectasia and chronic lymphocytic leukemia [CLL], respectively).

What is an elevated gamma globulin level?

Hypergammaglobulinemia is a medical condition with elevated levels of gamma globulin. It is a type of immunoproliferative disorder.

What is non familial hypogammaglobulinemia?

Description of Non-familial hypogammaglobulinaemia. Non-familial hypogammaglobulinaemia: Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.

What does polyclonal increase in gamma globulin levels mean?

A polyclonal increase in gamma globulins represents a normal defensive reaction by the body and can therefore be observed in infections such as viral hepatitis, chronic inflammatory diseases, autoimmune diseases, cirrhosis, etc.

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