What is nanocrystalline hydroxyapatite?

What is nanocrystalline hydroxyapatite?

Nanocrystalline hydroxyapatite (NHA) is a biocompatible, biodegradable, and osteoconductive bone graft material; however, it lacks osteoinductivity. Bone morphogenic protein 2 (BMP2), an osteoinductive growth factor, was incorporated into NHA (BMP2-NHA) using a simple adsorption method.

What is synthetic hydroxyapatite?

Synthetic hydroxyapatite (HA, general formula Ca10(PO4)6(OH)2) is a material commonly used in biomaterial engineering and regenerative medicine for bones [1], [2]. It displays high biocompatibility with biological apatite, the main component of the mineral fraction of bones and dental tissues.

What are the main hydroxyapatite in bone?

Bone mineral Hydroxyapatite consists of predominantly calcium and phosphate in a hexagonal crystal system and has the formula Ca10(PO4)6(OH)2. The hydroxyl ion can be replaced by fluoride, chloride or carbonate.

Is hydroxyapatite synthetic or natural?

Hydroxyapatite, also called hydroxylapatite (HA), is a naturally occurring mineral form of calcium apatite with the formula Ca5(PO4)3(OH), but it is usually written Ca10(PO4)6(OH)2 to denote that the crystal unit cell comprises two entities. Hydroxyapatite is the hydroxyl endmember of the complex apatite group.

How strong is hydroxyapatite?

Pure HA has bending, compressive, and tensile strength is in the range of 38 to 250 MPa, 120 to 150 MPa, and 38 to 300 MPa, respectively. Young’s modulus varies from 35 to 120 GPa, depending on the impurities[19]. Whereas, Weibull’s modulus with value in the range 5 to 18 exhibits that HA is a brittle material.

Which connective tissue contains hydroxyapatite?

Bone. Bone is the hardest connective tissue. It provides protection to internal organs and supports the body. Bone’s rigid extracellular matrix contains mostly collagen fibers embedded in a mineralized ground substance containing hydroxyapatite, a form of calcium phosphate.

Why is hydroxyapatite in baby powder?

Uses of hydroxyapatite powder in Cosmetics It is to be notified that these make the products help in either moisturizing the skin or softening the skin of the babies. It is also present in the makeup kits as their initial purpose is to provide moisture and softness to the skin.

Should I take hydroxyapatite?

Products that contain it have benefits for teeth that are lacking minerals from the enamel and are showing pre-cavity lesions. Regular use of hydroxyapatite products can help healthy teeth stay healthy and avoid becoming demineralized in the first place.

What are the side effects of calcium hydroxyapatite?

INFREQUENT side effects

• constipation.
• nausea.
• intense abdominal pain.