What is nicotine titration?

What is nicotine titration?

Compensatory smoking or nicotine titration is well documented in the tobacco smoking population; when given lower nicotine cigarettes, smokers increase their inhalation by taking more frequent and longer puffs or consuming more cigarettes (Ashton et al.

What are the non aqueous titration?

Non aqueous titration refers to a type of titration in which the analyte substance is dissolved in a solvent which does not contain water. proton donation with other weak acids and bases dissolved in it.

Which drugs can be determined by Alkalimetric non aqueous titration?

ALKALIMETRY IN NON-AQUEOUS TITRATIONS The wide spectrum of such organic compounds in-clude : anhydrides, acids, amino acids, acid halides, enols (viz., barbiturates), xanthines, sulphonamides, phenols, imides and lastly the organic salts of inorganic acids.

What are non aqueous titrations give two examples?

Examples- sulfuric acid, formic acid etc. Amphiprotic Solvents – These solvents have properties of both protophilic and protogenic solvents. Examples – alcohol, acetic acid etc.

What are the types of indicators for non aqueous titration?

Indicators used for non-aqueous titrations are:

• Crystal Violet: It gives violet colour in a basic medium and yellowish-green in acidic.
• Oracet Blue B: Blue colour in basic medium and pink in acidic.
• Alpha naphtholbenzein and quinaldine red are also used as indicators.

What is the scope of non aqueous titration?

Scope of Acetonitrile as a Solvent in the Nonaqueous Titration of Organic Medicinals. Its scope as a solvent must be investigated for each individual compound, since solubility cannot be predicted on the basis of chemical similarity.

Which is the valid reason for non aqueous titration?

The need for non-aqueous titration arises because water can behave as a weak base and a weak acid as well, and can hence compete in proton acceptance or proton donation with other weak acids and bases dissolved in it.

Which indicators are used in non aqueous titration?

What is non aqueous titration advantages and disadvantages?

Their types of solvents such as Protogenic Solvents and Amphiprotic Solvents etc… Advantage of Non-aqueous titration like is Non aqueous titration are accurate and Disadvantage like Solvent are expensive.

What is the meaning of non aqueous?

Definition of nonaqueous : not aqueous : of, relating to, or having the characteristics of a liquid other than water a nonaqueous solvent : made from, with, or by means of a liquid other than water nonaqueous solutions.

What types of indicators can be used in non aqueous titration?

Which indicator is used for non aqueous titration?

The important indicator used for non-aqueous titration are follow:- 1. Crystal voilet:- It is used as 0.5% solution in glacial acetic acid, it gives voilet colour in basic medium and yellowish green in acidic medium. It is most widely use for the titration of pyridine with prechloride acid. 2.

What is the importance of non-aqueous titration in pharmacology?

This procedure is a very important one in pharmacopoeial assays. The need for non-aqueous titration arises because water can behave as a weak base and a weak acid as well, and can hence compete in proton acceptance or proton donation with other weak acids and bases dissolved in it.

What is the Bronsted-Lowry theory of titration?

Many reactions which occur in non-aqueous titration procedures can be explained via the Bronsted-Lowry Theory and its definition of acids and bases. Basically, acids can be thought of as proton donors, whereas bases can be thought of as proton acceptors.

What are the different types of non aqueous solvents?

Types of Non Aqueous Solvents. Typically, there exist four types of solvents used in the non-aqueous titration of a given analyte. These are: Aprotic Solvents – these solvents are neutral in charge and are chemically inert.