What is OptiGen testing in dogs?

What is OptiGen testing in dogs?

OptiGen is a private company originally organized to access Cornell University biotechnology. Its sole focus is DNA-based veterinary diagnostics with test offerings for a growing list of canine vision diseases.

What does it mean if a dog is a carrier of CEA?

Collie eye anomaly (CEA) is a congenital, inherited, bilateral eye disease of dogs, which affects the retina, choroid, and sclera. It can be a mild disease or cause blindness. CEA is caused by a simple autosomal recessive gene defect. There is no treatment.

Do all Collies have CEA?

Collie Eye Anomaly (CEA) The disorder is found in rough and smooth collies of all colors worldwide, as well as other similar breeds including Border Collies, Shetland Sheepdogs, and Australian Shepherds.

What is CEA in Australian shepherds?

Collie Eye Anomaly (CEA), also known as choroidal hypoplasia (CH), is an inherited disease affecting several dog breeds including the Australian shepherd. In dogs affected with CEA, the choroid does not develop properly and is therefore thinner than normal. The severity of the condition can vary from dog to dog.

How do you test for MDR1 in dogs?

A test for the MDR1 mutation is available through the laboratory that first discovered the mutation, the Veterinary Clinical Pharmacology Laboratory at Washington State University (vcpl.vetmed.wsu.edu). The test can be performed with a cheek swab test kit or EDTA whole blood.

Is collie eye anomaly progressive?

Collie eye anomaly (CEA) is a congenital, non-progressive, ocular disease with variable manifestations (4).

How do you test for Collie Eye Anomaly?

A thorough eye examination is the frist step in diagnosing collie eye anomaly. Funduscopy, which examines the retina or bakc portion of the eyeball’s interior using an ophthalmoscope, is also used. Other possible causes of eye issues or blindess like disease, infection or injury must be ruled out.

What is trapped neutrophil syndrome?

Trapped neutrophil syndrome is an inherited neutropenia in Border Collies that compromises the immune system, leading to chronic infection in affected dogs.

How do you test for MDR1 mutation?

Can vets test for MDR1?

There is a commercially-available test that assesses blood samples or a cheek swab for the presence of the MDR1 mutation. Ask your veterinarian about this test if your dog is a herding breed, or if you otherwise suspect the possibility of MDR1 mutation.

What tests are included in the Optigen test?

Tests for Optigen prcd-PRA and Collie Eye Anomaly included at no additional charge. These tests are offered under exclusive license from the Cornell Research Foundation. Testing for 40+ traits including coat colors, coat types, and morphology. Genetic diversity information for the tested dog put into context for their breed.

How do you test for CEA in collies?

Animal Genetics offers DNA testing for Collie Eye Anomaly (CEA). The genetic test verifies the presence of the recessive CEA mutated gene and presents results as one of the following: Submit a Sample for Testing: To submit a sample for testing please go to Canine Test Now.

What is the CEA test used to diagnose?

The test can often help predict whether the cancer is growing or spreading to other parts of your body. It can also help tell how well your treatment has worked and predict your outlook. Your doctor might give you a CEA test if you’re diagnosed with one of these cancers: Bladder. Breast. Colon and/or rectal. Lung. Ovarian.

How many copies of the CEA gene does a dog have?

The dog carries two copies of the mutant gene and is homozygous for the CEA. The dog will be affected to some degree by Collie Eye Anomaly, and will always pass a copy of the mutated gene to its offspring. Both the normal and mutant copies of the gene detected.