What is replisome complex?
What is replisome complex?
Definition. The replisome is a large protein complex that carries out DNA replication, starting at the replication origin. It contains several enzymatic activities, such as helicase, primase and DNA polymerase and creates a replication fork to duplicate both the leading and lagging strand.
What is primosome complex?
In molecular biology, a primosome is a protein complex responsible for creating RNA primers on single stranded DNA during DNA replication. The primosome consists of seven proteins: DnaG primase, DnaB helicase, DnaC helicase assistant, DnaT, PriA, Pri B, and PriC.
What is replisome and primosome?
Biology Glossary search by EverythingBio.com. The DNA-replicating structure at the replication fork consisting of two DNA polymerase III enzymes and a primosome (primase and DNA helicase).
How does a replisome work?
The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.
Why is a replisome useful?
The replisome is a multiprotein molecular machinery responsible for the replication of DNA. It is composed of several specialized proteins each with dedicated enzymatic activities, and in particular, helicase unwinds double-stranded DNA and DNA polymerase catalyzes the synthesis of DNA.
What is the replicon?
A segment of the eukaryotic genome that contains several genes and is replicated as a unit from a single origin. replication is bi-directional; its boundaries are the points where replication from one origin meets the replication fork which advances from the opposite direction.
What does DnaA stand for?
DNAA
| Acronym | Definition |
|---|---|
| DNAA | Delayed Neutron Activation Analysis |
| DNAA | Durham and Northumberland Archery Association (UK) |
| DNAA | Driffield Navigation Amenities Association (UK) |
| DNAA | Defective DNA of the Bacteria Escherichia Coli |
Why is replisome important?
The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized.
What is the product of replisome?
The replisome is the DNA copy machine that contains helicases to unwind the DNA duplex, polymerases to copy the DNA, as well as nucleases and ligases to process the discontinuous stretches of DNA on the lagging strand (Bell & Dutta, 2002).
