What is selegiline hydrochloride used for?

What is selegiline hydrochloride used for?

Selegiline is used to help control the symptoms of Parkinson’s disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) in people who are taking levodopa and carbidopa combination (Sinemet).

Does selegiline help dogs sleep?

The most common type of sleep medication given to pets is diazepam (Valium®), although longer acting benzodiazepines may be used (eg temazepam). The symptoms of cognitive dysfunction are sometimes treated with a drug called selegiline. This is a type of drug called a mono-amine oxidase B (MAO-B) inhibitor.

Can I stop giving my dog selegiline?

The most common side effects are mild gastrointestinal upset, including nausea, vomiting, loss of appetite, and diarrhea. If these persist, your veterinarian may recommend stopping the selegiline for a few days and then re-starting at a lower dose.

Why is selegiline prescribed for Parkinson’s disease?

Eldepryl (selegiline) is used to help control the symptoms of Parkinson’s disease by increasing the amount of dopamine in the brain. Dopamine is a naturally occurring substance that is needed to control movement and its levels are reduced in people with Parkinson’s.

Who should not take selegiline?

Do not take selegiline if you have used narcotic pain medicines (including meperidine, methadone, tramadol, Demerol®, Dolophine®, Ultram®) or an MAO inhibitor (MAOI) (eg, isocarboxazid, linezolid, phenelzine, tranylcypromine, Marplan®, Nardil®, Parnate®, Zyvox®) within the past 14 days.

Does selegiline help with anxiety in dogs?

Clomipramine and selegiline have been approved for the treatment of separation anxiety in dogs, but there are anecdotal reports that they produce inconsistent therapeutic effect.

How long does selegiline stay in a dog’s system?

This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.

How long can you take selegiline for?

Adults—At first, 1.25 milligrams (mg) once a day before breakfast, for at least 6 weeks. After 6 weeks, your doctor may increase your dose to 2.5 mg once a day. Children—Use and dose must be determined by your doctor.

What type of drug is selegiline hydrochloride?

Selegiline Hydrochloride is the hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylaminewith antiparkinsonian effect. As a selective monoamine oxidase (MAO) inhibitor, selegilinehas the greatest affinity for type B MAO, found mainly in the brain.

What is selegiline (L-deprenyl)?

Twenty patients with mild-moderate pathological cerebral involution of atrophic and/or vascular origin, were treated with Selegiline ( L-deprenyl ), a monoamino-oxidase B inhibitor (10 mg/day for six months).

What is deprenyl used to treat?

A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.

What are the side effects of the selegiline patch for depression?

The main side effects of the patch form for depression include application-site reactions, insomnia, diarrhea, and sore throat. The selegiline patch carries a black box warning about a possible increased risk of suicide, especially for young people, as do all antidepressants since 2007.