What is SOMAscan assay?

What is SOMAscan assay?

SOMAscan is an aptamer-based proteomics assay capable of measuring 1,305 human protein analytes in serum, plasma, and other biological matrices with high sensitivity and specificity.

How does Somalogic work?

A single platform for discovery, validation, and delivery The SomaScan Assay uses Slow Off-Rate Modified Aptamers (called SOMAmer reagents) to provide 7,000 highly reproducible measurements of circulating proteins from a single sample of plasma, serum, or urine.

What is a SOMAmer?

SOMAmers are short, single stranded deoxyoligonucleotides. Like aptamers, they are selected in vitro from large random libraries for their ability to bind to discrete molecular targets, which can be small molecules, peptides, or proteins [4], [5].

Why are proteins studied collectively?

Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins.

What is a Somascan priest?

The Somascan Fathers are a charitable religious congregation of priests and brothers, founded in Italy in the 16th century by Saint Jerome Emiliani and named after the motherhouse at Somasca. They are often called Somascans for short.

What do you mean by proteomics?

Proteomics is the analysis of the entire protein complement of a cell, tissue, or organism under a specific, defined set of conditions. Proteomics is critically dependent on bioinformatics to process the raw mass spectral data into protein data.

Where is SomaLogic located?

Boulder, Colorado
SomaLogic is a protein biomarker discovery and clinical diagnostics company located in Boulder, Colorado.

When was SomaLogic founded?

2000
SomaLogic/Founded
SomaLogic was founded in 2000 by Larry Gold, with the long-term goal of transforming health care by empowering individuals around the world to actively optimize and maintain their health.

When did SomaLogic go public?

September 2, 2021
When did SomaLogic go public? SomaLogic went public on September 2, 2021.

What is a proteomic analysis?

Definition. Proteomic analysis (proteomics) refers to the systematic identification and quantification of the complete complement of proteins (the proteome) of a biological system (cell, tissue, organ, biological fluid, or organism) at a specific point in time.

What is a proteomic screen?

(PROH-tee-OH-mik PROH-file) Information about all proteins that are made in blood, other body fluids, or tissues, at certain times. A proteomic profile may be used to find and diagnose a disease or condition and to see how well the body responds to treatment.

Can I start a religious order?

Anyone, religious or lay, can start a religious community, but for it to be recognized canonically by the Catholic church and to be able to call themselves a Catholic organization they need to go through their local bishop and a set of parameters.

What is the Somascan assay?

Somalogic’s SOMAscan Assay allows for the simultaneous detection of 1,300 human proteins using SOMAmer (Slow Off-rate Modified Aptamer) protein-binding reagents. The assay is capable of detecting proteins in μM to fM concentrations by using dilutions of highly specific SOMAmers that bind to their cognate proteins.

What is the log range of the Somascan reagent?

10 log range Each SOMAmer reagent averages a 4.7 log dynamic range, but a tiered dilution approach is used to measure proteins… 125 fM The tiered approach used for SomaScan measurements enables detection of very rare proteins consistently without sample pre-treatment…

How many FM is Somascan?

125 fM The tiered approach used for SomaScan measurements enables detection of very rare proteins consistently without sample pre-treatment… 7,000 analytes By far the largest commercial proteomic assay on the market, the SomaScan assay provides over 7,000 unique protein measurements…