What is standard therapy for SLE?

What is standard therapy for SLE?

Nowadays, antimalarials are the basic treatment for every patient with SLE, whereas glucocorticoids should only be used when acutely indicated. If reduction or tapering of glucocorticoids proves impossible, extended immunosuppression with azathioprine, methotrexate, or mycophenolate mofetil is recommended.

What is the best treatment for SLE?

Hydroxychloroquine (Plaquenil) is the most common antimalarial for lupus. If you can’t take hydroxychloroquine, your doctor may recommend chloroquine (Aralen®). These medicines can be taken as pills or liquids.

What is the first line treatment for lupus?

Hydroxychloroquine is first-line treatment unless contraindicated and is useful in almost all manifestations of lupus. Other treatments are titrated against type and severity of organ involvement.

Is there any treatment of SLE?

No cure for SLE exists. The goal of treatment is to ease symptoms. Treatment can vary depending on how severe your symptoms are and which parts of your body SLE affects.

What test is used for lupus?

The test you will hear about most is called the antinuclear antibodies test (the ANA test). 97% of people with lupus will test positive for ANA. ANA connect or bind to the nucleus or command center of the cell. This process damages and can destroy the cells.

What infusion is given for lupus?

BENLYSTA is available as an intravenous (IV) infusion for patients ≥5 years old with lupus and adults with active lupus nephritis. You may prefer to receive BENLYSTA from your healthcare provider. Infusions are usually given at a doctor’s office or an infusion center.

Is dapsone used to treat lupus?

Small series have reported that dapsone, which has been used in the treatment of lupus since 1978, can ameliorate vasculitis, bullae, urticaria, oral ulcerations, thrombocytopenia, lupus panniculitis, and subacute cutaneous lupus. Dapsone may be steroid-sparing and can be effective in lupus resistant to chloroquine.

How does hydroxychloroquine work in SLE?

Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus (SLE).

What is infusion treatment for lupus?

Infusion therapy provides IV medications to patients who can’t be treated orally. The medication is given via an infusion pump into a catheter in your vein. Also called IV therapy, infusion therapy is quick to distribute the medicine — with treatments lasting anywhere from 25 minutes to several hours.

No cure for SLE exists. The goal of treatment is to ease symptoms. Treatment can vary depending on how severe your symptoms are and which parts of your body SLE affects. The treatments may include: Talk with your doctor about your diet and lifestyle habits.

How is SLE treated?

Treatment of systemic lupus erythematosus (SLE) is guided by the individual patient’s manifestations. Fever, rash, musculoskeletal manifestations, and serositis generally respond to treatment with hydroxychloroquine, nonsteroidal anti-inflammatory drugs ( NSAIDS ), and steroids in low to moderate doses, as necessary, for acute flares.

How to treat SLE?

Treating SLE often requires a team approach because of the number of organs that can be affected. SLE treatment consists primarily of immunosuppressive drugs that inhibit activity of the immune system. Hydroxychloroquine and corticosteroids (e.g., prednisone) are often used to treat SLE.