What is Synflorix injection?

What is Synflorix injection?

Synflorix is a vaccine that protects against infections caused by S. pneumoniae. Vaccines work by ‘teaching’ the immune system (the body’s natural defences) to defend the body against the infection.

Which is better synflorix or Prevnar 13?

The pneumococcal conjugate vaccine is safe. In most cases, it does not cause any reactions. The Synflorix® vaccine generally causes slightly fewer reactions than the Prevnar 13® vaccine.

Can Synflorix vaccine be given to adults?

As Synflorix™ is not intended for use in adults, adequate human data on use during pregnancy and lactation and adequate animal reproduction studies are not available. Not relevant. Clinical trials involved the administration of 12,879 doses of Synflorix™ to 4,595 healthy children as primary vaccination.

Who makes synflorix?

GlaxoSmithKline (GSK) today received European Commission authorisation for Synflorix™, a paediatric pneumococcal vaccine to protect against life-threatening diseases such as meningitis and bacteraemic pneumonia, as well as middle ear infections.

When do you give Synflorix vaccine?

Synflorix Vaccine is indicated to be used in infants and children from the age of 6 weeks up to 5 years against diseases caused by the organism called Streptococcus pneumoniae, such as pneumonia, meningitis, blood infection and ear infection.

How long does synflorix last?

Shelf Life: Synflorix should be administered as soon as possible after being removed from the refrigerator. However, stability data generated indicate that Synflorix remains stable and can be administered when the vaccine has been stored outside the refrigerator for up to 72 hours at temperatures between 8°C and 25°C.

What is the difference between Prevenar and Synflorix?

» All age groups, including young infants, respond well to this type of vaccine. » Synflorix includes 10 pneumococcal bacteria types, and can indirectly protect against two additional types. » Prevenar 13 includes the same pneumococcal types as Synflorix, plus three additional types.

Is synflorix a conjugate vaccine?

SYNFLORIX™ is a 10-valent pneumococcal conjugate vaccine (PCV-10) (containing serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, 23F) which has had Marketing Authorisation (MA) in Europe since 2009.

Is synflorix PCV13?

Synflorix (PCV10) and Prevenar 13 (PCV13) are conjugate vaccines. » Polysaccharide (sugar) molecules from the outside of pneumococcal bacteria have been attached (conjugated) to a protein to make them better at stimulating the immune system.

How do you inject Synflorix vaccine?

Use of Synflorix and other pneumococcal conjugate vaccines The vaccine should be given by intramuscular injection. The preferred sites are anterolateral aspect of the thigh in infants or the deltoid muscle of the upper arm in young children.

Can Infanrix cause fever?

What is the risk associated with Infanrix hexa? The most common side effects with Infanrix hexa (seen in more than 1 in 10 doses of the vaccine) are swelling, pain and redness at the injection site, loss of appetite, fever of 38ºC or more, tiredness, abnormal crying, irritability and restlessness.

Which is better PCV10 or PCV13?

Conclusion. Both PCV10 and PCV13 were immunogenic and induced a booster response. Compared to the PCV10 group, the PCV13 group showed higher levels for serotype 19F GMCs and avidity, pre- as well as post-booster, although opsonophagocytosis did not differ significantly between groups.