What is the classification of amiodarone?
What is the classification of amiodarone?
Amiodarone is in a class of medications called antiarrhythmics. It works by relaxing overactive heart muscles.
What class of drug is dofetilide?
Dofetilide is a class III antiarrhythmic agent (table 1) available for the acute termination of atrial fibrillation or flutter, as well as prevention of atrial fibrillation or flutter recurrence. Dofetilide has also been used in an off-label manner to treat paroxysmal supraventricular tachycardias.
What class is propafenone?
Propafenone is in a class of medications called antiarrhythmics. It works by acting on the heart muscle to improve the heart’s rhythm.
What class is sotalol?
Sotalol, a methanesulfonanilide, is a class III antiarrhythmic drug (table 1) that is used for the treatment of both atrial and ventricular arrhythmias. Sotalol was originally approved by the FDA (tradename Betapace) for the treatment of life-threatening ventricular arrhythmias.
What class antiarrhythmic is amiodarone?
Although amiodarone is considered a class III anti-arrhythmic agent, it also has class I, II, IV actions, making it a unique and effective anti-arrhythmic agent.
What are the 4 classes of antiarrhythmic drugs?
Antiarrhythmic drug classes:
- Class I – Sodium-channel blockers.
- Class II – Beta-blockers.
- Class III – Potassium-channel blockers.
- Class IV – Calcium-channel blockers.
- Miscellaneous – adenosine. – electrolyte supplement (magnesium and potassium salts) – digitalis compounds (cardiac glycosides)
What class of drug is diltiazem?
Diltiazem is in a class of medications called calcium-channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart.
What class of antiarrhythmic is quinidine?
Quinidine is a stereoisomer of quinine; it is a “class 1a antiarrhythmic drug” and also an antimalarial agent. As an “Antiarrhythmic”[1]: Atrial fibrillation (AFib) (safe and efficacious in combination with verapamil for the treatment of atrial fibrillation. Atrial flutter.
What class of drug is flecainide?
Flecainide is in a class of medications called antiarrhythmics. It works by slowing electrical signals in the heart to stabilize the heart rhythm.
What are the classes of antiarrhythmic drugs?
Is sotalol a Cardioselective?
Sotalol is a non-cardioselective beta-blocker that also possesses potassium channel blocker properties. It classifies as a class III agent in the Vaughan-Williams classification system for antiarrhythmic medications due to its predominant potassium channel blocking effect.
What drug class is digoxin?
Digoxin belongs to the class of medicines called digitalis glycosides. It is used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of the hands and ankles in patients with heart problems.
What class of drug is ibutilide?
Ibutilide is a class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion. Ibutilide is a Class III antiarrhythmic agent available in intravenous formulations.
What is the mechanism of action of ibutilide?
Ibutilide’s unique mechanism works by an activation of a specific inward sodium current, thus producing its therapeutic response in which a prolonged action potential increases myocytes’ cardiac refractoriness in case of atrial fibrillation and flutter. Ibutilide is intravenously administered.
What should I know about ibutilide before taking it?
Ibutilide can cause life-threatening irregular heart rhythms. Your heart rate will be constantly monitored using an electrocardiograph or ECG (sometimes called an EKG) so that any further problems can be treated quickly. You should not receive this medication if you are allergic to ibutilide.
What is the distribution of ibutilide in clinical trials?
Ibutilide has a relatively large volume of distribution among individual subjects, which is about 11L/kg. Approximately 40% of the drug is bound with plasma albumin of healthy volunteers in a trial. This is also approximately close to patients with atrial fibrillation and flutter.
