What is the difference between sevoflurane and desflurane?
What is the difference between sevoflurane and desflurane?
Sevoflurane has a blood: gas partition coefficient of 0.65, which is slightly greater than desflurane. The major advantage over desflurane is the better scent. It is considered to be less airway irritation in LMA anesthesia with smooth induction and recovery.
What is the difference between isoflurane and sevoflurane?
Sevoflurane is more suitable than isoflurane for single-breath induction, because it produces a smoother induction with a lower incidence of complications and better patient acceptance. Single-breath inhalation of a volatile anesthetic produces rapid induction of anesthesia without the need for intravenous drugs.
Which is most pungent isoflurane sevoflurane or desflurane?
Our results show that during a 60‐s inhalation of a 2 MAC concentration, sevoflurane is the least irritating anaesthetic agent. Isoflurane is more irritating than sevoflurane, but less so than desflurane, which seems to be unacceptably pungent. Most patients (20 out of 27) objected strongly to the inhalation.
What are the characteristics of sevoflurane?
SEVOFLURANE (fluoromethyl 2,2,2-trifluoro-l-[trifluoromethyl] ethyl ether), an inhalational anesthetic agent, has a low blood-gas partition coefficient (0.6–0.7) and a pleasant, nonpungent odor and provides a rapid, smooth induction and a rapid emergence from anesthesia in adults.
When do we use desflurane?
Inhaled desflurane is used to cause general anesthesia (loss of consciousness) before and during surgery in adults. It is also used as a maintenance anesthesia in adults and children after receiving other anesthetics before and during surgery.
What is the MAC of desflurane?
Background: The minimum alveolar concentration (MAC) of desflurane/oxygen is 7.25% in the 18-30-yr age group, and 6.0% in the 31-65-yr age group. The addition of 60% N2O reduces MAC to 4.0 and 2.83%, respectively.
Is sevoflurane more potent than isoflurane?
Sevoflurane is less potent than halothane and isoflurane. inhalant. The less potent the inhalant anesthetic, the higher the percentage of the inhalant anesthetic agent that will have to be used for anesthesia maintenance, and therefore the higher cost. roughly 200% – it is twice as potent in humans).
Why is chili called pungent?
The pungent feeling caused by allyl isothiocyanate, capsaicin, piperine, and allicin is caused by activation of the heat thermo- and chemosensitive TRP ion channels including TRPV1 and TRPA1 nociceptors. The pungency of chilies may be an adaptive response to microbial pathogens.
Is desflurane a pungent?
Desflurane has a strong pungent odor and is highly irritating to the airways (Rampil et al., 1991; van Hemelrijck et al., 1991). Among infants and children undergoing inhalation induction with desflurane without premedication, severe laryngospasm occurred in 73% of patients (Fisher and Zwass, 1992).
How is desflurane used?
Desflurane belongs to the group of medicines known as general anesthetics. Inhaled desflurane is used to cause general anesthesia (loss of consciousness) before and during surgery in adults. It is also used as a maintenance anesthesia in adults and children after receiving other anesthetics before and during surgery.
What is the density of desflurane?
Physical properties
| Boiling point : | 23.5 °C or 74.3 °F | (at 1 atm) |
|---|---|---|
| Density : | 1.465 g/cm³ | (at 20 °C) |
| Molecular Weight : | 168 | |
| Vapor pressure: | 88.5 kPa | 672 mmHg |
| 107 kPa | 804 mmHg |
When is sevoflurane used?
Sevoflurane is used to cause general anesthesia (loss of consciousness) before and during surgery. It is inhaled (breathed in). Although sevoflurane can be used by itself, combinations of anesthetics are often used together. This helps produce more effective anesthesia in some patients.
Does desflurane have a transient advantage over sevoflurane?
At fifth and fifteenth minutes, significantly higher percentages of patients in the desflurane group had recovery scores of ≥ 10. Desflurane offers a transient advantage compare with sevoflurane with respect of early recovery even though the duration of anaesthesia was longer in the desflurane group.
Is sevoflurane effective for supratentorial expanding lesions in neurosurgical patients?
Sevoflurane has been extensively used in neurosurgical patients. In this prospective clinical trial, we compared early postoperative recovery and cognitive function in patients undergoing craniotomy for supratentorial expanding lesions and receiving sevoflurane or desflurane anesthesia.
Does desflurane promote cerebral vasodilatation?
Desflurane in neurosurgery may be beneficial because it facilitates postoperative early neurologic evaluation. However, its use has been debated because of its capacity to promote cerebral vasodilatation. Sevoflurane has been extensively used in neurosurgical patients.
What are the side effects of sevoflurane in children?
However, sevoflurane has an irritating effect on the central nervous system, leading to frequent postoperative agitation ( 11 ). Agitation may cause the tearing of the operative wound in children, and physical harm to them.
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