What is the gene number of ATG8?
What is the gene number of ATG8?
852200
852200 – Gene ResultATG8 ubiquitin-like protein ATG8 []
Which chromosome is Drosophila?
Female Drosophila have two X chromosomes and males have one X and one Y. The X chromosome (also sometimes referred to as the first chromosome) is slightly larger than a single arm of chromosome 2 or 3 and very nearly acrocentric. The heterochromatic Y chromosome is divided into short (YS) and long (YL) arms.
Is ATG8 LC3?
ATG8/LC3 family: expression & structure. Yeast Atg8, is an ubiquitin-like (Ubl) protein, exhibiting amino acid sequence similarity with LC3 (A, B, C), GABARAP, GABARAPL1(GEC1), GABARAPL2 (also known as GATE-16 (Golgi-associated ATPase enhancer of 16 kDa)), and GABARAPL3 (Fig.
What is strange about Drosophila chromosomes?
THE dot chromosome, or F element, of Drosophila melanogaster is unique in that it has many characteristics of heterochromatin, yet maintains a typical euchromatic gene density in its 1.3-Mb long arm. The basic karyotype of Dipterans consists of six distinct genomic elements, named A through F by Muller (1940).
How is ATG7 related to autophagy?
Autophagy related 7 is a protein in humans encoded by ATG7 gene. During the initiation of autophagy, ATG7 acts like an E-1 enzyme for ubiquitin-like proteins (UBL) such as ATG12 and ATG8. ATG7 helps these UBL proteins in targeting their molecule by binding to them and activating their transfer to an E-2 enzyme.
How many pairs of chromosomes are in Drosophila?
It has only four pairs of chromosomes – three autosomes, and one pair of sex chromosomes.
Where are the Drosophila chromosomes located?
These chromosomes are found in several cell types, the function of which is principally secretory. In Drosophila, the most useful are found in the larval salivary glands.
What is the known function of ATG8?
For example, ATG8 proteins regulate membrane elongation during autophagosome biogenesis. Moreover, they play a crucial role in cargo recognition for selective autophagy by interacting with autophagy receptors/adaptors. In addition to their autophagic roles, ATG8 proteins play non-autophagic roles in plants.
Where is ATG8 located?
cytoplasm
Like most Atg proteins, Atg8 is localized in the cytoplasm and at the PAS under nutrient-rich conditions, but becomes membrane-associated in case of autophagy induction. It then localizes to the site of autophagosome nucleation, the phagophore-assembly site (PAS).
What is strange about the chromosomes of Drosophila compared to most other eukaryotic chromosomes?
Drosophila telomeres use arrays of retrotransposons to maintain chromosome length, while nearly all other eukaryotes rely on telomerase-generated short repeats. Regardless of the DNA sequence, several end-binding proteins are evolutionarily conserved.
How many pairs of chromosomes does the Drosophila have?
four pairs
It has only four pairs of chromosomes – three autosomes, and one pair of sex chromosomes. Males do not show meiotic recombination, facilitating genetic studies.
