What is the imidazole ring?
What is the imidazole ring?
Imidazole is a planar 5-membered ring. It exists in two equivalent tautomeric forms, because hydrogen can be bound to one or the other nitrogen atom. Imidazole is a highly polar compound, as evidenced by its electric dipole moment of 3.67 D. It is highly soluble in water.
Which method is used for synthesis of imidazole?
The dicarbonyl component is commonly glyoxal, but can also include various 1,2-diketones and ketoaldehydes. The method is used commercially to produce several imidazoles….
| Debus-Radziszewski imidazole synthesis | |
|---|---|
| Named after | Heinrich Debus Bronisław Leonard Radziszewski |
| Reaction type | Ring forming reaction |
Which amino acid has an imidazole ring give its structure?
Histidine
Histidine, an essential amino acid, has as a positively charged imidazole functional group. The imidazole makes it a common participant in enzyme catalyzed reactions.
How much nitrogen is present in imidazole ring?
1 Introduction. Imidazole 1 is a five-membered aromatic molecule containing two annular nitrogen atoms. One nitrogen behaves like a pyrrole-type nitrogen and the other one shows a close resemblance to a pyridine-type nitrogen.
What is structure of imidazole?
C3H4N2
Imidazole/Formula
What is the chemical structure of imidazole?
Imidazole
| PubChem CID | 795 |
|---|---|
| Structure | Find Similar Structures |
| Chemical Safety | Laboratory Chemical Safety Summary (LCSS) Datasheet |
| Molecular Formula | C3H4N2 |
| Synonyms | imidazole 1H-Imidazole 288-32-4 Glyoxaline Imidazol More… |
What is the chemical formula of imidazole?
What is the structure of imidazole?
What is thiazole ring?
Thiazole, or 1,3-thiazole, is a heterocyclic compound that contains both sulfur and nitrogen; the term ‘thiazole’ also refers to a large family of derivatives. The thiazole ring is notable as a component of the vitamin thiamine (B1).
What is pyrrolidine ring?
The pyrrolidine ring structure is present in numerous natural alkaloids such as nicotine and hygrine. It is found in many drugs such as procyclidine and bepridil. It also forms the basis for the racetam compounds (e.g. piracetam, aniracetam).
What is the Iupac name of imidazole?
| IUPAC Name | 1H-imidazole |
|---|---|
| Alternative Names | imidazole Glyoxaline 1,3-Diazole |
| Molecular Formula | C3H4N2 |
| Molar Mass | 68.079 g/mol |
| InChI | InChI=1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5) |
What is the structure and properties of imidazole?
STRUCTURE AND PROPERTIES:-. Imidazole is a monoacidic base having the ability to form crystalline salts with acids. The melting point of number of characteristic imidazolium salts [12]. Imidazole is a 5-membered planar ring, which is soluble in water and other polar solvents.
What is the role of urea-zncl2 in the formation of imidazoles?
The low-melting mixture urea-ZnCl 2 as reaction medium efficiently catalyzes the formation of imidazoles from a dicarbonyl compound, ammonium acetate, and an aromatic aldehyde to provide a broad range of triaryl-1 H -imidazoles or 2-aryl-1 H -phenanthro [9,10- d ]imidazoles in very good yields.
How can I synthesize 1h-imidazoles?
A one-pot, four-component synthesis of 1,2,4-trisubstituted 1H-imidazoles was achieved in very good yields by heating a mixture of a 2-bromoacetophenone, an aldehyde, a primary amine, and ammonium acetate under solvent-free conditions.
Why is the imidazole ring more prone to nucleophilic substitution reaction?
While the imidazole ring is rather susceptible to electrophilic attack on an annular carbon, it is much less likely to become involved in nucleophilic substitution reaction unless there is a strongly electron withdrawing substituent’s elsewhere in the ring. In the absence of such activation the position most prone to nucleophilic attack is C-2.
