What is the meaning of rabeprazole?
What is the meaning of rabeprazole?
Medical Definition of rabeprazole : a proton pump inhibitor that inhibits gastric acid secretion and is taken orally in the form of its sodium salt C18H20NaN3O3S especially to treat gastroesophageal reflux disease, duodenal ulcers, and disorders (such as Zollinger-Ellison syndrome) involving gastric acid hypersecretion.
What kind of drug is rabeprazole?
Rabeprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.
What are the characteristics of rabeprazole?
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug – in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
What is the generic name for rabeprazole?
Aciphex is available as generic termed rabeprazole sodium.
Who makes Rabeprazole?
Learn more about Rabeprazole Sodium | Lannett Company.
Who should not use Rabeprazole?
Before Using Use of rabeprazole for treating gastroesophageal reflux disease (GERD) is not recommended in children younger than 1 year of age for Aciphex® Sprinkle™ capsule or in children younger than 12 years of age for Aciphex® delayed-release tablets.
Who should not use rabeprazole?
What is mode of action of rabeprazole?
Mechanism Of Action Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds.
What is difference between omeprazole and rabeprazole?
No significant differences in laboratory parameters were seen. Conclusion: In this study, rabeprazole produced healing rates comparable to omeprazole at weeks 3 and 6, but provided more consistent and occasionally significantly superior symptom improvement. Both treatments were well-tolerated.
What is difference between pantoprazole and rabeprazole?
Conclusions: In GERD patients with nocturnal heartburn, rabeprazole 20 mg was significantly more effective than pantoprazole 40 mg in percentage time with intragastric pH >4 during the nighttime, daytime, and 24-h periods. Differences between treatments in OAE were not demonstrated.
