What is the normal range of HBV DNA quantitative?
What is the normal range of HBV DNA quantitative?
Normal range for this assay is Not Detected. The quantitative range of this assay is 1.00-9.00 log IU/mL (10-1,000,000,000 IU/mL).
How is HBV DNA measured?
The HBV DNA test is performed on a blood sample using a Polymerase Chain Reaction (PCR) technique that rapidly generates HBV DNA fragments so they can be measured. Today, viral load is usually measured using international units per milliliter (IU/mL).
How do you interpret Hep B viral load?
In a person with detectable HBeAg, an HBV viral load greater than 20,000 international units per milliliter (IU/mL) of blood indicates that the virus is active and has the greatest potential to cause damage to the liver.
What is HBV DNA viral log?
The hepatitis B virus DNA quantification, also known as the viral load test, is a blood test that measures the amount of hepatitis B virus DNA (viral load) in the blood of chronically infected patients. The blood is tested using a Polymerase Chain Reaction (PCR) technique.
What is HBV IU mL?
A quantitative result expressed in IU/mL and log IU/mL indicates the degree of active HBV viral replication in the patient. Monitoring HBV DNA levels over time is important for assessing disease progression or monitoring a patient’s response to anti-HBV therapy.
What is a low viral load for hep B?
In particular, patients with serum HBV DNA levels ≥ 2000 IU/mL at study entry have an increased risk of developing HCC over time. In contrast, those with HBV DNA levels < 2000 IU/mL are usually designated as low viral load patients.
What is the normal range of hepatitis B viral load?
HBV: Hepatitis B virus. # Normal values: ALT: Males: 10-40 U/L; Females: 7 – 35 U/L; AST: Males: 15 – 40 U/L; Females: 13 – 35 U/L. HBeAg-positive patients had significantly higher ALT levels (mean 170.3 ± 391 IU/L) compared to HBeAg-negative patients (mean 53.9 ± 169.4 IU/L), p < 0.0001 (Table 2).
What is a normal HBV viral load?
How do you convert IU mL to mL?
International units are traceable to CMV DNA WHO International Standard (NIBSC 09/162) and conversion factor is 1 IU/mL = 1.72 copies/mL.
What is log10 HBV IU mL?
A result of “<10 IU/mL (<1.00 log IU/mL)” indicates that HBV DNA is detected, but the HBV DNA level present cannot be quantified accurately below this lower limit of quantification of this assay. When clinically indicated, follow-up testing with this assay is recommended in 1 to 2 months.
What is a good viral load count?
What the Results Mean. A high viral load is generally considered about 100,000 copies, but you could have 1 million or more. The virus is at work making copies of itself, and the disease may progress quickly. A lower HIV viral load is below 10,000 copies.
How to convert HBV/mL to IU/ml?
I would be thankful to you, if you please convert 191.710^5 copies HBV/ml into IU/ml. Looking for your reply. For HBV viral load conversion, 1 IU/ml = 5.6 copies/ml. So 191.7 x 10 (5) = 19,170,000 copies = 3.5 million IU/mL.
How is the HBV DNA test performed?
The HBV DNA test is performed on a blood sample using a Polymerase Chain Reaction (PCR) technique that rapidly generates HBV DNA fragments so they can be measured. Today, viral load is usually measured using international units per milliliter (IU/mL).
What is the normal range of HBV DNA?
When the levels of HBV DNA are less than 4.0 log copies/mL, the risk of progression to cirrhosis is low. However, the risk of cirrhosis is reported to increase with an increase in the levels of HBV DNA above 4.0 log copies/mL [5]. Similarly, HBV DNA levels at the start of observation are thought to be associated with hepatocarcinogenesis.
What is undetectable HBV viral load?
An undetectable viral load (which means fewer HBV DNA than a lab’s equipment can identify) generally is lower than about 300 copies/mL. Moderate levels of HBV DNA begin at about 10,000 to copies/mL.
