What is the virulence factor of gonorrhea?
What is the virulence factor of gonorrhea?
Like many Gram-negative bacterial pathogens, N. gonorrhoeae possesses a wide range of virulence determinants, which include the elaboration of pili, Opa protein expression, lipooligosaccharide expression (LOS), Por protein expression and IgA1 protease production that facilitates adaptation within the host.
What is the pathogenesis of gonorrhea?
Pathogenesis of Neisseria gonorrhoeae and the Host Defense in Ascending Infections of Human Fallopian Tube. Neisseria gonorrhoeae is an obligate human pathogen that causes mucosal surface infections of male and female reproductive tracts, pharynx, rectum, and conjunctiva.
What are the different types of virulence factors?
Specific Virulence Factors
- Adherence and Colonization Factors. To cause infection, many bacteria must first adhere to a mucosal surface.
- Invasion Factors.
- Capsules and Other Surface Components.
- Endotoxins.
- Structure of Endotoxin.
Is gonorrhea gram-negative?
a mucopurulent endocervical or urethral exudate on physical examination and. sexual exposure to a person infected with N. gonorrhoeae….Definitions: Identification of N. gonorrhoeae.
| Characteristic | Illustration |
|---|---|
| Gram stain Cell Morphology | Gram-negative diplococcus |
What is the differential diagnosis of gonorrhea?
Gonorrhea must be differentiated from other sexually transmitted pathogens, nongonococcal urethritis, vaginitis, cervicitis, urinary tract infections, prostatitis, and orchitis.
What are the virulence factors of Streptococcus pyogenes?
GAS strains express many virulence factors including surface protein M, streptolysins, streptokinase, hyaluronidase, peptidoglycan, and teichoic acid. Protein M is considered as the main virulence factor, limiting phagocytosis, disturbing the function of complement, and being responsible for adhesion [4].
What is the pathogenesis of Chlamydia?
Disease pathogenesis due to Chlamydia trachomatis is a complicated process that involves: (1) exposure to the organism and infectivity; (2) survival within the host cell; (3) virulence associated with specific strain types; (4) innate and acquired immunity, and (5) host genetic susceptibility to infection and disease.
How do you diagnose Chlamydia?
Tests include:
- A urine test. A sample of your urine is analyzed in the laboratory for presence of this infection.
- A swab. For women, your doctor takes a swab of the discharge from your cervix for culture or antigen testing for chlamydia. This can be done during a routine Pap test.
