What must be administered prior to succinylcholine?
What must be administered prior to succinylcholine?
If a small dose of pancuronium is given at least 3 minutes before administration of succinylcholine, in order to reduce the incidence and intensity of succinylcholine-induced fasciculations, this dose may induce a degree of neuromuscular block sufficient to cause respiratory depression in some patients.
What should be monitored when taking phenelzine?
Hepatologists may be necessary to test hepatic function because phenelzine may cause hepatotoxicity. Primary care clinicians and psychiatrists must monitor for serotonin syndrome, tyramine-induced hypertensive crisis, and dose-related orthostatic hypotension.
What is the mechanism of action of phenelzine?
The basic mechanism of action of phenelzine acts as an inhibitor and substrate of monoamine oxidase which subsequently causes an elevation in brain levels of catecholamines and serotonin.
What are the adverse effects of phenelzine?
Phenelzine may cause side effects. Tell your doctor if any of the following symptoms are severe or do not go away:
- drowsiness.
- weakness.
- dizziness.
- dry mouth.
- constipation.
- weight gain.
- decreased sexual ability.
- uncontrollable shaking of any part of the body.
Who should not receive succinylcholine?
Succinylcholine is contraindicated in persons with personal or familial history of malignant hyperthermia, skeletal muscle myopathies, and known hypersensitivity to the drug.
When do you not give succinylcholine?
The administration of succinylcholine chloride is contraindicated in patients with known decreased plasma cholinesterase activity, recent burns or trauma within 24 to 72 hours, and muscle myopathies.
What can you not take with phenelzine?
Avoid smoked or pickled meat, poultry, or fish, such as sausage, pepperoni, salami, anchovies, or herring. Do not eat dried fruit (such as raisins), bananas, avocados, raspberries, or very ripe fruit. Do not drink alcoholic beverages.
Is phenelzine an antagonist?
Phenelzine as a stimulant drug antagonist: a preliminary report.
What does phenelzine help with?
Phenelzine is used to treat certain types of depression. It belongs to the group of medicines called monoamine oxidase inhibitors (MAOI). This medicine works by blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system.
What is the major risk for a client who is taking phenelzine and citalopram?
Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or …
Is succinylcholine contraindicated in pregnancy?
Thus succinylcholine is an ideal neuromuscular blocker in pregnant females because it provides an excellent intubation conditions along with a short duration of apnea, although it has been observed that the duration of action of succinylcholine is significantly longer in pregnant women as compared with nonpregnant …
Does succinylcholine interact with benzodiazepines?
The absence of an interaction does not necessarily mean no interactions exist. The risk or severity of adverse effects can be increased when Succinylcholine is combined with 1,2-Benzodiazepine. The risk or severity of hyperkalemia can be increased when Succinylcholine is combined with Acebutolol.
What are the side effects of succinylcholine and aminophenazone?
The metabolism of Succinylcholine can be decreased when combined with Ambenonium. The risk or severity of hyperkalemia can be increased when Succinylcholine is combined with Amiloride. The risk or severity of hyperkalemia can be increased when Succinylcholine is combined with Aminophenazone.
What is the mechanism of action of succinylcholine?
The mechanism of action of Succinylcholine involves what appears to be a “persistent” depolarization of the neuromuscular junction. This depolarization is caused by Succinylcholine mimicking the effect of acetylcholine but without being rapidly hydrolysed by acetylcholinesterase. This depolarization leads to desensitization.
Can succinylcholine and alfentanil be taken together?
The risk or severity of hyperkalemia can be increased when Succinylcholine is combined with Alclofenac. The risk or severity of bradycardia can be increased when Succinylcholine is combined with Alfentanil. The risk or severity of adverse effects can be increased when Succinylcholine is combined with Alimemazine.
