When do you cover anaerobes?

When do you cover anaerobes?

Anaerobic coverage may be indicated in various infections including but not limited to intra-abdominal infections, aspiration pneumonia, diabetic foot infections/osteomyelitis, and gynecologic infections.

Does meropenem have anaerobic coverage?

Meropenem and imipenem were the most active agents tested. On the basis of these results, meropenem appears to be a promising antimicrobial agent for anaerobic infections and warrants further clinical investigation.

What does Pip Tazo not cover?

They do NOT cover: MRSA, VRE, Atypicals, among others. Zosyn (Piperacillin/Tazobactam) – broader due to excellent anaerobe coverage, activity vs Amp-susceptible Enterococcus. No ESBL coverage.

Does Flucloxacillin cover anaerobes?

Flucloxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria.

Do fluoroquinolones cover anaerobes?

Overall, the newer fluoroquinolones were found to be highly active against anaerobic bacteria, including Fusobacterium, Peptostreptococcus, and Prevotella species, with a majority of isolates requiring MICs of <1.0 µg/mL (table 1).

What group of antibiotic is clindamycin?

Clindamycin is in a class of medications called lincomycin antibiotics. It works by slowing or stopping the growth of bacteria.

Does doxycycline cover anaerobic bacteria?

Doxycycline has a broad spectrum of activity and is effective against gram-positive and gram-negative, aerobic and anaerobic bacteria, spirochetes, and mycoplasma.

Which antibiotics cover anaerobes?

The most effective antimicrobials against anaerobic organisms are metronidazole, the carbapenems (imipenem, meropenem and ertapenem), chloramphenicol, the combinations of a penicillin and a beta-lactamase inhibitor (ampicillin or ticarcillin plus clavulanate, amoxicillin plus sulbactam, and piperacillin plus tazobactam …

Does doxycycline cover E coli?

Doxycycline is indicated for treatment of infections caused by the following gram-negative microorganisms, when bacteriological testing indicates appropriate susceptibility to the drug: Escherichia coli. Enterobacter aerogenes (formerly Aerobacter aerogenes).

What is the plasma concentration of cefotetan?

Cefotetan is 88% plasma protein bound. No active metabolites of Cefotetan have been detected; however, small amounts (less than 7%) of Cefotetan in plasma and urine may be converted to its tautomer, which has antimicrobial activity similar to the parent drug.

What are the contraindications for cefotetan?

Cefotetan is contraindicated in patients with a known allergy to the cephalosporin group of antibiotics and in those individuals who have experienced a cephalosporin associated hemolytic anemia.

When to stop taking cefotetan for anemia?

Cefotetan should be discontinued until etiology is determined if anemia develops within 2 or 3 weeks of initiation of therapy. Patients should be advised to avoid alcohol for at least 3 days after cefotetan use in order to avoid possible disulfiram-like reaction.

What is cefotetan used to treat?

Because of its antimicrobial spectrum, cefotetan is used to treat lower respiratory tract infections, GU tract infections, skin infections, septicemia, and surgical prophylaxis. Cefotetan appears effective and safe during pregnancy for the treatment of acute infections.