Where are the receptors for NGF located?
Where are the receptors for NGF located?
retina
NGF has two receptors named high affinity NGF tyrosine kinase receptor TrkA and low affinity receptor p75NTR. Both receptors exist in cells in retina like RGC (expressing TrkA) and glia cells (expressing p75NTR). NGF functions by binding to TrkA or p75NTR alone or both together.
How does NGF affect gene expression in nerve cells?
Neuronal proliferation NGF can drive the expression of genes such as bcl-2 by binding to the Tropomyosin receptor kinase A, which stimulates the proliferation and survival of the target neuron. High affinity binding between proNGF, sortilin, and p75NTR can result in either survival or programmed cell death.
Which type of neuron is associated with dorsal root ganglion?
pseudo-unipolar type
The neurons comprising the dorsal root ganglion are of the pseudo-unipolar type, meaning they have a cell body (soma) with two branches that act as a single axon, often referred to as a distal process and a proximal process.
What are visceral motor neurons?
Visceral efferent neurons are motor neurons that conduct impulses to smooth muscle, cardiac muscle, & glands. These neurons make up the Autonomic Nervous System. Some visceral efferent neurons begin in the brain; others in the spinal cord.
What type of neuron is in the dorsal root ganglion?
The neurons comprising the dorsal root ganglion are of the pseudo-unipolar type, meaning they have a cell body (soma) with two branches that act as a single axon, often referred to as a distal process and a proximal process.
What does the NGF do?
The NGF gene provides instructions for making a protein called nerve growth factor beta (NGFβ). This protein is important in the development and survival of nerve cells (neurons), especially those that transmit pain, temperature, and touch sensations (sensory neurons).
What is NGF gene?
What functional type of neuron is found in the dorsal root ganglion quizlet?
What functional type of neuron is found in the dorsal root ganglion? This is the second motor neuron. It is sometimes called the Ganglionic neuron.
