Which drug is more effective Gleevec imatinib or dasatinib?

Which drug is more effective Gleevec imatinib or dasatinib?

Collectively, these results suggest that dasatinib has greater potency than imatinib against the BCR-ABL kinase17,20,21 and show that dasatinib has an efficacy profile that is superior to that of imatinib among patients with newly diagnosed chronic-phase CML.

Who should not take imatinib?

Do not use imatinib if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 14 days after your last dose.

What cancers is imatinib used for?

This medication is used to treat certain types of cancer (such as acute lymphoblastic leukemia, chronic myeloid leukemia, gastrointestinal stromal tumors, and myelodysplastic/myeloproliferative diseases). It works by slowing or stopping the growth of cancer cells.

How long does it take for imatinib to work?

Using RECIST, the median time to response is approximately 3 months, and median time to disease progression on imatinib is about 2 years.

What happens if I stop taking imatinib?

Update on Stopping Imatinib in CML A total of 61% of patients lost undetectable minimal residual disease at a median of 2.5 months after discontinuation of imatinib for CML; no recurrences occurred after 22 months.

Does imatinib weaken your immune system?

Imatinib appears to block a protein called Ido, which researchers think tumors use to promote regulatory T cell function and thus prevent immune attack. Neutralizing Ido’s effect alters the ratio among the T cells, giving the cytotoxic T cells the upper hand to unleash the immune response.

Is imatinib an immunotherapy?

Immunotherapy with monoclonal antibodies, such as ipilimumab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Imatinib mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Do you lose your hair with imatinib?

In most cases, the drug is well tolerated: however, side effects can be seen. Hair loss and paronychia inflammation were often reported with Imatinib, but total alopecia was rarely mentioned. We report a CML patient who was presented with alopecia and paronychia inflammation probably induced by imatinib therapy.

Can you drink on imatinib?

Avoid grapefruit and grapefruit juice for the duration of your treatment, as these may interact with imatinib. The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of imatinib.

Is Gleevec a chemotherapy drug?

How Gleevec chemotherapy is given and possible side effects. Gleevec for the treatment of Chronic Myeloid Leukemia. Gleevec (Imatinib) is a drug used to treat chronic myeloid leukemia.

Is Gleevec considered chemotherapy?

Any drug used to treat cancer can be considered chemo – even the targeted therapy drugs like imatinib (Gleevec) that are now commonly used to treat gastrointestinal stromal tumors (GISTs).

Is there a generic for Gleevec?

A generic version of Gleevec has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available – possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Gleevec and have been approved by the FDA:

Can Gleevec cause kidney problems?

Renal failure is found among people who take Gleevec, especially for people who are male, 60+ old , have been taking the drug for 1 – 6 months, also take medication Allopurinol, and have Gastrointestinal stromal tumor.