Which of the following software is used for pharmacokinetics?
Which of the following software is used for pharmacokinetics?
Commercial Software
| Commercial Softwares | Description |
|---|---|
| DATAKINETICS | Pharmacokinetics Dosing program |
| Kinetica | fast high-throughput data analysis for clinical, preclinical, discovery, drug metabolism and drug delivery settings. |
| PDx-IVIVC | |
| PK Solutions | easy, interactive, comprehensive pharmacokinetic analysis |
What is PK PD assays?
Pharmacokinetic-Pharmacodynamic (PKPD) analysis is an alternative to conventional dose-effect analysis, and it relates drug effects to a measure of drug concentration in a body compartment (e.g., venous blood) rather than to drug dose.
What is QSP model?
Quantitative systems pharmacology (QSP) is a field of biomedical research that aims to model the mechanisms behind disease progression and quantify the pharmacokinetics and pharmacodynamics of pharmaceuticals using mathematical computer models.
What is PK PD data?
PKPD analysis is an alternative to conventional dose-effect analysis of in vivo drug effects, and it focuses on the relationship of drug-induced behavioral or physiological effects to drug and metabolite concentrations in the body rather than to drug dose.
What does fT MIC mean?
Three major PD indices – the percent of time that free drug remains above the MIC over a 24-hour period (fT>MIC), the ratio of free drug area under the concentration-time curve to MIC over a 24-hour period (fAUC:MIC), and the ratio of maximum concentration to MIC (Cmax:MIC) – sufficiently link the kinetics of …
What is the duration of a drug?
The duration of action of a drug is the length of time that particular drug is effective. Duration of action is a function of several parameters including plasma half-life, the time to equilibrate between plasma and target compartments, and the off rate of the drug from its biological target.
What is AUC mic?
AUC:MIC – A combination of both T>MIC and Peak:MIC. The rate of bacterial killing is both related to the amount of time above the MIC and the total exposure of antibiotic to the organism.
What is PD analysis?
Pharmacodynamics (PD) analysis allow drug developers to quantify the relationship between the drug dose and the pharmacologic or toxicologic effect it has on patients. The results of PD studies can often be impacted by the response of the receptor.
