Which one is the example of benzofuran derivative?

Which one is the example of benzofuran derivative?

This colourless liquid is a component of coal tar. Benzofuran is the “parent” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants….Benzofuran.

What is the use of benzofuran?

Benzofuran derivatives are an important heterocyclic compounds that are possess vital biological activities such as antidepressant, anticancer, antiviral, antifungal, antioxidant, anti-psychotic etc.

Is benzofuran aromatic?

Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.

Is benzofuran soluble in water?

Air & Water Reactions Very slightly water soluble.

Is furan an aromatic compound?

Furan and Furan-Related Compounds. Furan is an aromatic compound with the participation of the oxygen lone pair in the π-electron system to satisfy Hückel’s rule, 4n + 2 (n = 1) electrons. The compound is stable to heating up to about 550°C (depending also on heating time).

Which heterocyclic ring is present in furosemide?

Furosemide is a chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.

What is the meaning of benzofuran?

Benzofuran. Benzofuran is the heterocyclic compound consisting of fused benzene and furan rings. This colourless liquid is a component of coal tar. Benzofuran is the “parent” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants.

What are the disadvantages of benzofurans?

Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids. Consequently, ring synthesis is often preferred <51JA754 > to electrophilic substitution.

Is benzofuran a heterocycle?

Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals [66].

What is the half life of benzofuran in air?

Vapor-phase benzofuran is also degraded in the atmosphere by reaction with ozone (4); the half-life for this reaction in air is estimated to be about 6 days (SRC). Benzofuran absorbs light in the environmental UV spectrum (absorption max = 285 nm) (5); thus it has the potential for direct photolysis (SRC).

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