Why is isoniazid abbreviated as H?
Why is isoniazid abbreviated as H?
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol….Isoniazid.
| Clinical data | |
|---|---|
| Routes of administration | By mouth, intramuscular, intravenous |
Why is tuberculosis abbreviated as TB?
Tuberculosis (TB) was called “phthisis” in ancient Greece, “tabes” in ancient Rome, and “schachepheth” in ancient Hebrew. In the 1700s, TB was called “the white plague” due to the paleness of the patients. TB was commonly called “consumption” in the 1800s even after Schonlein named it tuberculosis.
What is Z in TB drugs?
Anti-TB drugs are classified into 5 groups based on efficacy, experience of use and drug class….Anti-TB drugs.
| Group name | Anti-TB drug | Abbreviation |
|---|---|---|
| GROUP 1 First-line oral agents | Isoniazid Rifampicin Pyrazinamide Ethambutol Rifabutin | H R Z E Rfb |
Who is Inoniazid resistance?
The new guidelines recommend that patients with confirmed isoniazid-resistant and rifampicin susceptible tuberculosis (abbreviated to Hr-TB) are treated for 6 months with a regimen composed of rifampicin (R), ethambutol (E), pyrazinamide (Z) and levofloxacin (Lfx).
Which vitamin is administered with INH?
Vitamin B6 (pyridoxine) supplementation during isoniazid (INH) therapy is necessary in some patients to prevent the development of peripheral neuropathy.
Which is target of INH drug?
The preferred antitubercular drug isoniazid specifically targets a long-chain enoyl-acyl carrier protein reductase (InhA), an enzyme essential for mycolic acid biosynthesis in Mycobacterium tuberculosis. Despite the widespread use of this drug for more than 40 years, its precise mode of action has remained obscure.
What is the full form of BCG vaccination?
BCG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated.
What is Fixcom 4 used for?
Fixcom 4: For initial or intensive phase treatment of all forms of pulmonary and extrapulmonary tuberculosis.
WHO TB isoniazid?
Isoniazid (INH) is an important first-line anti-TB agent because of its potent early bactericidal activity. However, resistance to INH, alone or in combination with other drugs, is now the most common type of resistance to anti-TB drugs.
What should I know about isoniazid before taking it?
Some recommend that liver function should be monitored carefully in all people receiving it, but others recommend monitoring only in certain populations. Headache, poor concentration, weight gain, poor memory, insomnia, and depression have all been associated with isoniazid use.
What is isoniazid-resistant tuberculosis (TB)?
Isoniazid-resistant TB (Hr-TB), refers to Mycobacterium tuberculosis strains with resistance to isoniazid and susceptibility to rifampicin confirmed in vitro. Definitions and terms used herein have been described elsewhere.1,2 Poly-resistancerefers to resistance to more than one first-line anti-TB drug, other than isoniazid and rifampicin together.
Why do we use abbreviations for countries?
These short codes are intuitive so they can be used as a universal and instant informative representation for each country. These abbreviations are used in postal services, world currencies, travel and business activities, as well as web address identification. This list of countries and abbreviations was also published by the United Nations.
Is there a link between isoniazid and acetaminophen?
People taking isoniazid and acetaminophen are at risk of acetaminophen toxicity. Isoniazid is thought to induce a liver enzyme which causes a larger amount of acetaminophen to be metabolized to a toxic form.
