Is PDGF a mitogen?
Is PDGF a mitogen?
Platelet-derived growth factor (PDGF) is a potent mitogen, chemoattractant, and survival factor for cells of mesenchymal origin (such as fibroblasts, smooth muscle cells, or glial cells).
Is PDGF a chemokine?
Our data suggest that PDGF-mediated IL8 chemokine secretion and cell growth and migration in corneal fibroblasts occur via JAK2-STAT3 pathway.
What is PDGF-AA?
PDGF-AA (Platelet-Derived Growth Factor AA) is a widely expressed protein that forms disulfide linked homodimers or heterodimers with PDGF-B. PDGF-AA is expressed by monocytes, macrophages, fibroblasts, vascular smooth muscle cells, and vascular endothelial cells.
Is PDGF inflammatory?
These data suggest that PDGF signalling in VSMCs induces signals, likely to be chemokines, which create an inflammatory milieu in the wall of the thoracic aorta.
What is PDGF AA?
