What are the characteristics of FOP?

What are the characteristics of FOP?

Clinical Characteristics of FOP: Flare-ups that worsen the condition occur spontaneously or following viral illnesses or physical trauma to the muscle such as: intramuscular childhood immunizations, falls, surgery, biopsy. Rogue bone growth progressively restricts movement.

How long can you live with FOP?

Some people go months or even years without a flare-up. FOP can become severely disabling. Most people with FOP will need a wheelchair by the time they reach their late 20s. The median lifespan for people with FOP is 40 years .

What is the most common cause of FOP?

FOP is caused by the mutation of a gene (ACVR1) in the bone morphogenetic protein (BMP) pathway, which is important during the formation of the skeleton in the embryo and the repair of the skeleton following birth.

What does FOP feel like?

FOP flare-ups typically last 6 to 8 weeks. They may cause pain and swelling, stiffness in the joints, all-around discomfort, and a low-grade fever.

What does FOP disease do?

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder that causes soft tissues to transform permanently into bone. These bones grow abnormally in the muscles, tendons, ligaments and other connective tissues, forming bridges of extra bone across the joints.

Can you cure FOP?

Currently, there is no cure for FOP. Courses of high-dose corticosteroids at the start of a flare-up can reduce some of the symptoms of the condition.

How is FOP treated?

Who does FOP effect?

Worldwide, FOP affects only about 2,500 people, or one in 2 million, of all ethnicities, ages and races. Because FOP is such a rare disease, experts believe that 80 percent or more of the cases are misdiagnosed and its prevalence may be much higher than known.

What is fop disease?

Fibrodysplasia ossificans progressiva FOP: A rare disease but dramatic genetic disorder that turns muscles, tendons and ligaments into bone. Fibrodysplasia ossificans progressiva (FOP) is a condition in which bone grows outside the skeleton. Abnormal bone growth replaces connective tissue, including tendons and ligaments.

What are the needs of a child with FOP in school?

The needs of a child with FOP in a school setting have to do with gentle handling and preventing falls or bumps, as well as positioning the child so he/she can see, hear, and gain access to places (desk, floor) and school materials with the least amount of strain on his/her body as possible.

What is FOP (fibrodysplasia ossificans progressiva)?

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that causes human connective tissue to turn into bone. Here’s how it works. For decades, FOP was a medical curiosity, a disease without a treatment or even a biological explanation.

What is the primary FOP issue at this time?

This means that the primary FOP issue at this time is the overriding need to prevent trauma that may start a flareup.