Does atropine sulfate expire?
Does atropine sulfate expire?
According to the package insert, the original 1% atropine sulfate eye drops are described to be stable for at least 36 months before opening and 28 days after opening [9].
How long does atropine injection last?
Atropine
| Clinical data | |
|---|---|
| Metabolism | ≥50% hydrolysed to tropine and tropic acid |
| Onset of action | c. 1 minute |
| Elimination half-life | 2 hours |
| Duration of action | 30 to 60 min |
How long does atropine IV last?
Atropine is incompletely metabolised in the liver and is excreted in the urine as unchanged drug and metabolites. About 50% of the dose is excreted within 4 hours and 90% in 24 hours. The elimination half-life is about 2 to 5 hours.
How is atropine stored?
Storage. Store at 20° to 25°C (68° to 77°F). Keep tightly closed.
What happens if you use expired atropine?
Do not use Atropine Eye Drops after the expiry date printed on the pack. If you use it after the expiry date has passed, it may have no effect at all, or worse, there may be an entirely unexpected effect. Do not purchase or use Atropine Eye Drops if the packaging is torn or shows signs of tampering.
Should atropine be refrigerated?
Do not freeze the medicine. Keep the medicine away from light by storing it in the brown, zip-close bag provided by your pharmacist. Call your pharmacist if the medicine is not refrigerated for more than 30 minutes.
How often can I give atropine?
The dosing for Atropine is 1 mg IV every 3-5 minutes as needed, and the maximum total dosage for administration is 3 mg.
When should atropine be administered?
Atropine is the first-line therapy (Class IIa) for symptomatic bradycardia in the absence of reversible causes. Treatments for bradydysrhythmias are indicated when there is a structural disease of the infra-nodal system or if the heart rate is less than 50 beats/min with unstable vital signs.
When does atropine stop?
Atropine should be avoided with bradycardia caused by hypothermia and, in most cases, it will not be effective for Mobitz type II/Second-degree block type 2 or complete heart block.
When can atropine be administered?
How do you store atropine injections?
Atropine Injection will be stored in the pharmacy or on the ward. The injection is kept in a cool dry place, where the temperature stays below 25°C.
