What does P TEFb phosphorylation?
What does P TEFb phosphorylation? The Positive Transcription Elongation Factor b (P-TEFb) phosphorylates Ser2 residues of the C-terminal domain (CTD) of the largest subunit (RPB1) of RNA polymerase II and is essential for the transition from transcription initiation to elongation in vivo. What is promoter proximal pausing? Pol II pauses in the proximity of the […]